Optimization of Process Parameters for Improved Lipase Production by Hyperthermophilic Bacillus sonorensis 4R | Chapter 05 | Advances and Trends in Biotechnology and Genetics Vol. 2
Thermostable lipases isolated from thermophilic bacteria are emerged as industrially and biotechnologically important bio-molecules in recent era of globalization due to their potential to work at high temperatures. Knowledge of growth conditions and nutritional parameters controlling lipase production is necessary to improve its yield and successful development of an industrial bioprocess without increasing the cost of production. We are reporting the individual and interactive effects of process parameters on lipase production by a hyperthermo-alkalophilic strain of Bacillus sonorensis 4R. In the present study, the individual and combined effects of process parameters on lipase production by a hyperthermo-alkalophilic strain of B. sonorensis 4R are studied. Parameters used in this study were incubation period, temperature, initial pH of medium, carbon and nitrogen sources, substrates and metal salts. The isolate showed maximum lipase production after 4 days of incubation at 80°C a...