Tranexamic Coated or Eluted Uterine Balloon and Co Attached Cervical Shutter in Post Partum Haemorrhage. The First all in One Pharmaco-Mechanical Approach | Chapter 18 | New Frontiers in Medicine and Medical Research Vol. 3
The goal was to provide an economical, convenient gadget to the obstetrician's arsenal that includes all treatment techniques in one device with a feasible use, high efficacy, and safety, and a pharmacomechanical trinity of activities. A Tranexamic Acid (TXA) - Coated or Eluted Uterine Balloon is described herein for use in an intrauterine site for the primary therapy of postpartum haemorrhage (PPH). It augments the tamponade action of currently employed non-medicated uterine balloons with an inherent mechanism of local steady release of the antibrinolytic TXA into the uterine cavity, which has been shown to aid in haemostasis in PPH instances. The invention entails TXA coated or eluted balloons replenish non-medicated balloons with a TXA related – antifibrinolys therapeutic method, which is notably useful in haemorrhages linked with coagulopathy. This potential for TXA topical treatment rather than systemic injection has the benefit of eliminating the putative danger of thrombosis...