Contribution of Three (3) Medicinal Plants of Senegalese Flora in the Management of Sickle Cell Disease | Chapter 07 | Advances in Applied Science and Technology Vol. 4
Sickle cell disease is a major public health problem in Africa and many other areas across the world. Many drugs that are available for treating the disease are insufficiently effective, toxic, or too expensive. Therefore, there is a pressing need for safe, effective, and inexpensive therapeutic agents from indigenous plants used in traditional medicines. In Senegal, a lot of plants are proposed by traditional healers to manage the sickle cell disease, among them Combretum glutinosum, Leptadenia hastate and Maytenus senegalensis. These plants were studied in this work. Methanolic and ethyl acetate extracts of part of these plants were evaluated on SS sickles type to determine their anti-sickling potential. Antiradical properties of methanolic extract of C glutinosum were evalua...