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Showing posts with the label Adrenocortical carcinoma

An Unusual Case Presentation on Giant Non-Functioning Adrenocortical Carcinoma | Chapter 21 | New Horizons in Medicine and Medical Research Vol. 1

  A case of gigantic non-functioning adrenocortical carcinoma without pressure effects is shown here, which is a rare occurrence. Adrenocortical carcinoma is an uncommon tumour with a global incidence of 1 per million. The age distribution is bimodal, with maxima at 5-20 and 40-50 years old. Tumors that are larger than 9 cm frequently affect the inferior vena cava (IVC) or the right side of the heart. The carcinomas are functioning in 80% of cases. We present a case of a rare non-functioning adrenocortical carcinoma in a 40-year-old woman with an incidence of 0.5/million worldwide, no extra-adrenal dissemination at presentation, and no IVC or right ventricular involvement despite a tumour size of 12 cm. With regular follow-ups and disease-free life following the surgery, the patient had a successful surgical extirpation with adjuvant radiotherapy. Hormone levels in symptomatic and asymptomatic patients with adrenal masses must be determined. The possibility of adrenocortical carcin...