B P International

The goal of this study was to see if Lipp Stress Control Training can help people with metabolic syndrome. Metabolic syndrome is defined by the presence of several risk factors such as glucose intolerance, dyslipidemia, and hypertension, as well as poor diet, sedentariness, tobacco use, alcoholism, and excessive stress. The study included 45 older women with MetS who were between the ages of 60 and 75. Lipp Stress Control Training, comprising of eight two-hour sessions with five groups of eight persons, was provided to them once a week. After the session, stress levels were found to have fallen significantly (p=0.005). Before and after treatment, total cholesterol (p=0.012), LDL (p=0.0133), and triglycerides (p=0.05) were all significantly reduced in the group. Stress Control Training reduced some MetS risk factors, such as stress, and may have aided in the reduction of MetS components such as glucose, triglycerides, total cholesterol, and LDL cholesterol. If the current conclusions ar...

  For a long time, it was assumed that, while weight loss was necessary and desired, comorbidities were far more significant and required treatment, preferably with medication, even if weight loss was not a treatment objective. This disagreement causes therapy to be postponed, which then leads to overly extensive medical treatment. As a result, health-care expenses have risen to unacceptably high levels, resulting in the medicalization of individuals and a decline in patient responsibility for their own health, leaving it up to individuals to decide when their own weight is an issue that needs to be addressed. The goal of this study was to gather evidence to support a paradigm change in regards to the association between body weight and comorbidities. Insulin resistance is the root of the problem, which leads to a slew of other health issues. To ensure better tailor-made treatment for patients, this illness should be diagnosed at primary care and obesity clinics. Treatment for insu...

Background: If a person has metabolic syndrome, their risk of cardiovascular disease and type 2 diabetes mellitus is greatly elevated. In India, obesity and type 2 diabetes have become epidemics. Low-grade systemic inflammation characterises metabolic syndrome, which is a pro-inflammatory disease. C-reactive protein (CRP), a biomarker, is a reliable sign of chronic systemic inflammation. Higher levels of high sensitivity C-reactive protein (Hs-crp) have been associated to metabolic syndrome and its components, and can help predict future cardiovascular events. The following are the goals of the research: 1) The link between metabolic syndrome and high-sensitivity C reactive protein 2)An investigation of high-sensitivity C reactive protein as a surrogate measure of chronic inflammation in the metabolic syndrome. Methods and Materials The participants in this cross-sectional study included 50 patients with metabolic syndrome aged 18 and up, as well as 50 age and sex matched controls who ...

Adipose tissue is considered as an active endocrine organ that releases a large number of adipokines modulating blood pressure, glucose and lipid metabolism, inflammation, and atherosclerosis. Atherosclerosis has been found linked with various traditional and novel risk actors. This chapter describe the updated review of published literature and present research findings describing the linkage of extent and severity of coronary atherosclerosis with two of the adipokines, adiponectin and leptin, as novel risk factors in metabolic syndrome (MetS) patients. A pilot, Case-control study was carried under Sadbhavna Medical and Heart Institute, Patiala and, Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, between January to December 2013. MetS patients (n=55) with age ≥18 years, undergoing angiography for diagnosis and/or interventional treatment of atherosclerosis and 25 matched control subjects were recruited. Evaluation of traditional and novel cardi...

Aims: To investigate the endocrine-metabolic changes in postmenopausal women with MetS and examine relationship with the polymorphisms of eNOS-G894T, p22(phox)-930 A/G, CETP TaqIB, ESR1 (PvuII and XbaI) genes. Methods: 280 postmenopausal apparently healthy women aged between 60 and 80 years were classified into non-MetS (212) and MetS (68). Clinical, anthropometric and endocrine-metabolic parameters were measured. The single nucleotide polymorphisms were determined and tested for interacting with these parameters. Results: The weight, waist circumference, blood pressure, WBC, triglycerides, LDL-C, TG/HDL-C ratio, apolipoprotein (apo)B, apoB/apoA-I ratio, fasting glucose, insulin, HOMA, uric acid,   were higher and HDL-C was lower in MetS group thus   fulfilled the criteria for the MetS. The significant higher levels of E2, T3, GHBP, PTH and lower levels of cortisol, SHBG, FSH, LH, IGFBP1, cortisol/DHEA ratio were also detected. Genetic association stu...

The concept of metabolic Syndrome was first introduced as Syndrome X by Gerald Reaven He delivered the Banting Lecture in 1988 at the American Diabetes Association national meeting. He stated that Syndrome X is aggregation of independent, risk factors present in the same individual which are seen in coronary heart disease (CHD). The various risk factors included in the syndrome were insulin resistance, defined as the inability of insulin to optimally stimulate the transport of     glucose into the body’s cell (hyperinsulinemia or impared glucose tolerance, hypertension, hypertriglyceridemia, and low, high-density lipotrotein cholesterol (HDL) [1]. Syndrome X is referred as,the deadly quartet by Kaplan [2] and Foster described it as,a secret killer [3]. Reaven in his Banting Lecture described the point that insulin resistance/hyperinsulinemia might be the underlying cause of the syndrome. Reaven also suggested that insulin resistance/hyperinsulinemia was an underlying r...