B P International

 Background: Local pain after a Propofol injection is a common occurrence. Different ways have been tried to alleviate the discomfort, but they have had mixed results. The purpose of this study was to examine the efficacy of injection Dexmedetomidine 0.2 mcg/kg against injection Lignocaine 0.2 mg/kg in preventing pain caused by Propofol injection. Method: The study was started with written informed consent from the participants after receiving clearance from the Institutional Ethics Committee. In a randomised prospective trial, 60 ASA I and II patients between the ages of 20 and 60 years, of either sexe, were randomly assigned to one of two groups for elective procedures under general anaesthesia. Injection Dexmedetomidine 0.2mcg/kg in Group I (Dexmedetomidine group), and Injection Lignocaine 0.2 mg/kg in Group II (Lignocaine group). In 5 mL normal saline, both were diluted. A 20 G cannula was used to secure the IV line, and a pneumatic tourniquet was used to apply venous o...

Background: Intrathecal Bupivacaine is the most often used local anaesthetic for lower segment caesarean sections, but researchers are always exploring for new local anaesthetics with better safety profiles for both the mother and the foetus. Many adjuvants, such as fentanyl, morphine, or tramadol, have been used with intrathecal local anaesthetics in the past to prolong intraoperative anaesthesia and postoperative analgesia. There is no literature on the use of dexmedetomidine as an adjuvant with isobaric levobupivacaine. As a result, we wanted to see how dexmedetomidine and fentanyl performed in lower segment caesarean sections when paired with 0.5 percent isobaric intrathecal levobupivacaine in spinal anaesthesia. Methodology: Following clearance by the institutional ethical committee and informed written agreement, patients were divided into three equal groups: Group L will get 2.5 ml of 0.5 percent isobaric levobupivacaine, 5 g dexmedetomidine, and 25 g fentanyl intrathecally; G...

Background: Acute discomfort during the perioperative period is deleterious to the postoperative result, and appropriate analgesia improves the outcome. It raises the body's sympathetic response, resulting in increased oxygen consumption, increased risk of deep vein thrombosis due to immobility, and pulmonary embolism. Methods: Sixty ASA I/II patients between the ages of 18 and 65 who underwent laparoscopic cholecystectomy and appendicectomy were randomly assigned to one of two groups. Patients with an ASA III/IV rating, those who had already received opioid or alpha 2 agonist treatment, and those who needed substantial surgical dissection were excluded. Prior to extubation, Group D got 1 g/kg IV Dexmedetomidine over 10 minutes, followed by 0.2-0.7 g/kg/hr, while Group P received 15 mg/kg IV Paracetamol. After extubation, patients' hemodynamics were followed and their VAS scores were measured for the next 24 hours. The time interval between the requirement of the first dosage...