Squamous Cell Carcinoma of the Kidney and Renal Pelvis: A Review and Update of the Literature | Chapter 06 | New Insights into Disease and Pathogen Research Vol. 4
Background: Primary squamous cell carcinoma of renal pelvis/kidney (PSCCRP/K) is rare with controversies regarding its histogenesis. Aim: To review the literature. Methods: Various internet data bases were searched. Literature Review: Few cases of PSCCRP/K have been reported with only three cases of PSCC of the renal parenchyma without involvement of renal pelvis. Some PSCCRP/Ks have been associated with renal calculi, chronic infections, vesicoureteric reflux. Some cases had developed many years following successful percutaneous nephrolithotomy; a case was reported many years after curative radiotherapy for testicular tumour. The tumours are initially diagnosed in advanced stages; generally the prognosis has been poor following nephrectomy/nephrouretectomy. Conventional radiology imaging features of the disease are non-specific and cannot differentiate the lesion from other tumours or xanthogranulomatous pyelonephritis. Diagnosis is based upon strict histopathological c...