B P International

 Scrub typhus is a disease caused by Orientia tsutsugamushi and spread by trombiculid mites in India. In India, it is a common cause of acute febrile sickness. Fever, headache, myalgia, and GI symptoms are common signs and symptoms, and it's usually coupled with a morbilliform rash (40 percent) and eschar (50 percent) caused by the mite's bite. In the early stages of disease, abnormal LFTs and lymphocytosis are prevalent. It's commonly referred to as PUO. Early diagnosis and treatment results in a high rate of complete recovery. The goal of this study was to bring attention to the prevalence of scrub typhus at a tertiary care hospital in Kolkata, India. From May to December 2019, the authors assessed 100 individuals who had a fever, malaise, headache, with or without rash, for more than a week. Fever profiles (Dengue NS1 antigen, MP, MPDA, TyphidotM) and cultures were performed as part of routine blood tests. Patients with lymphocytosis, hyponatremia, and transaminitis ...

Introduction: In central nervous system (CNS), oligodendrocytes form myelin. In peripheral nervous system large proportions of axons are unmyelinated, instead they are ensheathed by non myelinating schwann cells   and   arranged   in   Remak   bundles.   Osmotic   demyelination   (ODS)   syndrome   is   a neurologic disorder that can occur after rapid correction of hyponatremia. Acute hypernatremia results in   sudden   shrinkage   of   brain   cells   leading   to   parenchymal   or   subarachnoid hemorrhages   and/or subdural hematomas mainly in pediatric patients. Aim: Our aim is to present a case of hypernatremia which has led on to a flaccid quadriparesis due to brain   stem   demyelination.   Rapid   correction   of   hypernatremia   as   a   cause   for   pyramidal   tract demyelination is not docume...