Family Risk of Metabolic Disorder; A Parameter for Timely Screening of Vascular Endothelial Health | Chapter 12 | New Insights into Disease and Pathogen Research Vol. 1
Aim: To study the correlation of vascular endothelial health with family risk of metabolic disorders, in healthy overweight, obese and non obese subjects. Study Design: A case-control (pilot) study. Place and Duration of Study: The study was conducted in Cardiovascular Physiology lab, Department of Physiology, K.G.M.U Methods: Cases and controls comprised from January 2009 to February 2010. of 30 overweight / obese healthy subjects (BMI >= 25 kg/m2 and/or WHR (female>0.85; male>1) and 30 non-obese healthy subjects respectively (BMI< 25 kg/m2 and/or WHR (female<0.85; male<1) excluding subjects with secondary cause of abnormal blood flow. Vascular endothelial health was assessed via reactive hyperemic response measured via impedance plethysmography in the subject’s forearm. Fasting plasma glucose and serum lipid profile was also done. Results: On comparison of biochemical variables, lipid derangem...