A Review on Rare Calciphylaxis Due to Primary Hyperparathyroidism | Chapter 7 | New Frontiers in Medicine and Medical Research Vol. 3
Calciphylaxis is a life-threatening disorder caused by mural calcification and thrombosis of arterioles and capillaries in the dermis and subcutaneous adipose tissue. It causes increasing skin ischemia and extremely painful cutaneous necrosis and ulceration. This frequently results in sepsis and multi-organ failure, with a high fatality rate. It is most common in individuals with end-stage renal disease (ESRD) who are on dialysis or have just had a kidney transplant. As a result, it's linked to secondary and tertiary hyperparathyroidism. This condition is known as uremic calciphylaxis. Non-uremic calciphylaxis is a similar rare condition that affects patients with normal renal function. In this article, we look at a rare case of calciphylaxis caused by primary hyperparathyroidism with normal renal function. Calciphylaxis is a life-threatening condition that causes sepsis and multi-organ failure, as well as a high rate of morbidity and fatality. Any patient with painful necrotic esc...