Total Antioxidants Status, Selenium Concentration, Catalase and Glutathione Peroxidase Activities in Rabbits Fed a High-Garlic Diet | Chapter 11 | Recent Advances in Biological Research Vol. 4
Aim: Results from previous studies on the effects of intake of garlic on the body antioxidant system appear inconclusive. This study measured glutathione peroxidase (GPx) and catalase (CAT) activities, Total Antioxidant Status (TAS) and selenium (Se) level in rabbits fed a high-garlic diet. Methods: Ten rabbits randomly assigned into two groups (group 1=control and group 2= test) of five rabbits each were used for the experiment. The diet of group 2 was mixed with raw garlic homogenate (1.75g/Kg body weight/day) for 4 weeks. Two sets of blood samples were collected from each animal at the beginning of the experiment (baseline) and at the end (4 weeks). Blood samples were analyzed for blood GPx and serum CAT activities and TAS by spectrophotometric methods while Se was determined using Atomic Absorption Spectrophotometric (AAS) method. Results: At baseline, means of the parameters measured did not differ significantly between groups 1 and 2. At the 4th week,...