B P International

For over two decades, research on the biological and analytical applications of calixarenes and their derivatives has been shown remarkable properties towards organic and bioorganic molecules. Applications in the field of analytical chemistry and biological activity, as well as the anticancer properties of various calixarenes, have been studied and reported by several research groups. Due to their superior geometrical shape, calix[n]arenes structures (with n = 4; 6 or 8) have a special function, moreover, when combined with functional groups, the calixarenes can dissolve well and the low toxicity of the cell and the ability to form stable complexes with metal ion, especially the ability to transport drugs, it is allowed to be applied in the analysis and development of biosensors in fields: Biotechnology and drug discovery calixarene derivatives. The applications of calixarenes and their derivatives are summarized in this review, and future development prospects will be discussed. Au...

It is estimated that there will be an increase in the incidence of chronic obstructive pulmonary disease (COPD) in the coming decades. Thus, the pharmacological attributes of products of plant origin should be considered as an important economic and scientific strategy in the investigation of therapeutic alternatives, since their experimental validations are indispensable to substantiate the reliability of these products in the treatment of chronic diseases. Like biologically active compounds, Eucalyptol, also known as 1,8- cineole, is the major constituent of the leaf oil of eucalyptus species, such as Eucalyptus globulus and Eucalyptus tereticornis. It is a terpenoid oxide, free of steroid-like side effects. This study is based on a review of the specialised literature with purpose to discuss the biological effects of Eucalyptol in the respiratory system and its interaction with some of the most promising targets in the treatment of COPD, such as: receivers and membrane channels,...