Association of Adiponectin and Leptin with Coronary Atherosclerosis Severity Indices in Metabolic Syndrome Patients | Chapter 07 | Emerging Research in Medical Sciences Vol. 3
Adipose tissue is considered as an active endocrine organ that releases a large number of adipokines modulating blood pressure, glucose and lipid metabolism, inflammation, and atherosclerosis. Atherosclerosis has been found linked with various traditional and novel risk actors. This chapter describe the updated review of published literature and present research findings describing the linkage of extent and severity of coronary atherosclerosis with two of the adipokines, adiponectin and leptin, as novel risk factors in metabolic syndrome (MetS) patients. A pilot, Case-control study was carried under Sadbhavna Medical and Heart Institute, Patiala and, Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, between January to December 2013. MetS patients (n=55) with age ≥18 years, undergoing angiography for diagnosis and/or interventional treatment of atherosclerosis and 25 matched control subjects were recruited. Evaluation of traditional and novel cardi...