Demyelinating Disorders of the Nervous System Due to Osmotic Disequilibrium | Chapter 04 | Current Trends in Medicine and Medical Research Vol. 4
Introduction: In central nervous system (CNS), oligodendrocytes form myelin. In peripheral nervous system large proportions of axons are unmyelinated, instead they are ensheathed by non myelinating schwann cells and arranged in Remak bundles. Osmotic demyelination (ODS) syndrome is a neurologic disorder that can occur after rapid correction of hyponatremia. Acute hypernatremia results in sudden shrinkage of brain cells leading to parenchymal or subarachnoid hemorrhages and/or subdural hematomas mainly in pediatric patients. Aim: Our aim is to present a case of hypernatremia which has led on to a flaccid quadriparesis due to brain stem demyelination. Rapid correction of hypernatremia as a cause for pyramidal tract demyelination is not docume...