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The Seroprevalence and Eradication Success of Helicobacter pylori in Indigenous People of Seletar in Southern Malaysia | Chapter 14 | New Insights into Disease and Pathogen Research Vol. 3

Background: Helicobacter pylori prevalence rate varies widely from one geographical area to another and marked differences have been noted among different ethnic groups. While several studies have been carried out to review the prevalence of H. pylori among the major races in Malaysia, only one is available to study the indigenous Penan community in East Malaysia. Aims: The aims of this study are to determine the seroprevalence of H. pylori in the indigenous Seletar community in Southern Malaysia and the effectiveness of the eradication program. Methods: A seroepidemiological study was done to determine H. pylori infection by serological assay of H. pylori antibodies and the demographic pattern. Serological assay was carried out using the Visual H. pylori Quickpac Test. All serological positive patients were then subjected to an endoscopic study and the Campylobacter-Like Organism-test (CLO-test). Positive patients were then offered for eradication using triple therapy of...

Potential Risk Factors and Prevalence of Infection of Helicobacter pylori in Nigeria | Chapter 14 | Theory and Applications of Microbiology and Biotechnology Vol. 1

Aim: Potential risk factors and prevalence associated with Helicobacter pylori (H. pylori) infection in apparently healthy children in Nigeria were studied. Study Design: To investigate the current potential risk factors associated with recent prevalence of H. pylori in apparently healthy children in Nigeria. Place and Duration of Study: The study was conducted in two Local Government Areas, Alimosho and Ajeromi, of Lagos State, Nigeria between March and September 2014. Methodology: Seroprevalence status of 185 asymptomatic children made up of 93 males and 92 females, aged between 2-16 years were selected by randomized stratified sampling with descriptive questionnaire. Serum immunoglobulin G H. pylori antibody of the individual subjects was determined using DiaSpot H. pylori kit while fecal samples of same group were analysed for HpSAg using immunoassay test kit of Helicobacter pylori Stool Antigen (HpSAg). Results: Of 185 children tested for H. pylori antigen, ...