Skip to main content

Potential Risk Factors and Prevalence of Infection of Helicobacter pylori in Nigeria | Chapter 14 | Theory and Applications of Microbiology and Biotechnology Vol. 1

Aim: Potential risk factors and prevalence associated with Helicobacter pylori (H. pylori) infection in apparently healthy children in Nigeria were studied.

Study Design: To investigate the current potential risk factors associated with recent prevalence of H. pylori in apparently healthy children in Nigeria.

Place and Duration of Study: The study was conducted in two Local Government Areas, Alimosho and Ajeromi, of Lagos State, Nigeria between March and September 2014.

Methodology: Seroprevalence status of 185 asymptomatic children made up of 93 males and 92 females, aged between 2-16 years were selected by randomized stratified sampling with descriptive questionnaire. Serum immunoglobulin G H. pylori antibody of the individual subjects was determined using DiaSpot H. pylori kit while fecal samples of same group were analysed for HpSAg using immunoassay test kit of Helicobacter pylori Stool Antigen (HpSAg).

Results: Of 185 children tested for H. pylori antigen, 134 (68.7%) and 51(26.2%) were classified as seropositive and fecal HpSA positive respectively. Highest rate of 40.0% and 34.6% of the children weighing between 21 and 40 kg were positive while 29.2% and 32.5% children of parents that were traders were positive to serum H. pylori antigen and fecal HpSA respectively. Only 12.4% and 14.1% children from artisan parents were positive but different age group have no association with the infectivity or prevalence of fecal H. pylori antigen (OR=0.67, CI=0.142-0.152). Significant higher percentage of seropositivity of 59.0% and fecal positivity of 55.7% was recorded among children from 5-8 people in a room (p>0.05), while Households with regular potable water supply have lower H. pylori seropositivity and fecal positivity of 11.9% and 7.6% compared with households that sometimes have water supply. The Households that never had water supply had highest number of seropositivity of 40.0% and 18.4%, respectively. Sewage nearness to kitchen indicates 30.8% and 28.7% H. pylori seropositive and fecal positivity rate among children.  

Conclusion: Paediatric H. pylori prevalence is highly associated with water borne infection and poor sanitary practices. There is need for achievable interventions and improvement in environmental sanitation.

Author(s) Details

F. O. Olufemi
Department of Veterinary Microbiology and Parasitology, College of Veterinary Medicine, Federal University of Agriculture, Nigeria.

Quadri Remi
Department of Microbiology, College of Biological Sciences, Federal University of Agriculture, Abeokuta, Nigeria.

P. A. Akinduti
Department of Veterinary Microbiology and Parasitology, College of Veterinary Medicine, Federal University of Agriculture, Nigeria.

S. A. Bamiro
Department of Physiology, College of Medicine, Lagos State University, Lagos, Nigeria.

Comments

Popular posts from this blog

Consensus Summit: Lipids and Cardiovascular Health in the Nigerian Population | Chapter 09 | Current Trends in Food Science Vol. 1

Aims: To issue a consensus statement on Lipids and Cardiovascular Health and the impact of their interrelationship in Nigerian Population. Study Design: Experts from a range of relevant disciplines, deliberated on different aspects of Lipids and Cardiovascular Health in the Nigerian Population at a Summit. Place and Duration of Study: The Summit was held in April 2016 at the Nigerian Institute of Medical Research. Methodology: Presentations were made on central themes after which expert participants split into four different groups to consider the questions relevant to different sub themes of the title. Consensus was arrived at, from presentations of groups at plenary. Conclusion: With the increase in the prevalence of NCDs, especially Cardiovascular Disease in Nigeria, and the documented evidence of deleterious effects of lipids, the expert panel called for an urgent need to advocate for the general public and health professionals to make heart-friendly

A Review on Gongronema latifolium, an Extremely Useful Plant with Great Prospects | Chapter 11 | Recent Advances in Biological Research Vol. 3

Gongronema latifolium is a plant that has a wide range of nutritional and ethnomedical uses in different tropical African communities. Scientific reports on the chemical composition and bioactivity (anti-inflammatory, antimicrobial, antidiabetic, antioxidant, anticancer and allelopathic properties) of the plant material by different authors are discussed in this review. Future prospects of the plant extracts in the areas of herbal formulations, food preservation, alcoholic fermentation and beer production, drug discovery and allelopathy are also highlighted. Author   Details: Olugbenga Morebise Faculty of Basic Medical Sciences, All Saints University School of Medicine, Roseau, Commonwealth of Dominica. Read full article: http://bp.bookpi.org/index.php/bpi/catalog/view/50/403/433-1 View Volume: https://doi.org/10.9734/bpi/rabr/v3

An Overview of Ultrasonic Technology and Its Applications in Food Processing, Preservation and Quality Control | Chapter 03 | Current Research in Science and Technology Vol. 3

Ultrasound is one of the emerging technologies that were developed to minimize processing, maximize quality and ensure the safety of food products. In recent years, ultrasound technology has been used as an alternative processing option to conventional thermal approaches. Although Ultrasonication methods have been used for years in research and diagnostics, major advances have been made in the last decade. The applications for which high power ultrasound can be used range from existing processes that are enhanced by the retrofitting of high power ultrasonic technology, to the development of processes up to now not possible with conventional energy sources. The present paper reviews the generation, principle mechanism, properties, process parameters, applications, merits and demerits and future trends of the ultrasound technology in the food processing. Author(s) Details Er. Bogala Madhu Department of Processing and Food Engineering, College of Technology and Engineering, MP