Training and Evaluation of a Knowledge-Based Model for Automated Treatment Planning of Multiple Brain Metastases: An Advanced Study | Chapter 3 | Highlights on Medicine and Medical Science Vol. 18
Aim: Due to its capacity to give steep dose gradients around targets as well as modest doses to essential structures, volumetric modulated arc therapy (VMAT) has been used to plan and treat numerous cranial lesion metastases utilising a single isocenter. When compared to employing a single isocenter for each lesion, VMAT treatment takes significantly less time. However, approaches to shorten treatment planning time for these patients while simultaneously standardising plan quality must be developed. In this paper, we show how to plan numerous cranial SRS cases using RapidPlan, a knowledge-based treatment (KBP) planning software. Methods: A model was trained using 66 patient plans with 125 lesions (range 1-4, median 1). In addition, the model was tested on 10 previously treated cases that were picked at random. For target coverage and critical organ dose, the clinical plans were compared to RapidPlan plans. Results: There was no significant difference in coverage to the target volum...