B P International

NENs (neuroendocrine neoplasms) are a diverse group of tumours with a neuroendocrine character. They range from well-differentiated neuroendocrine tumours (NETs) to aggressive neuroendocrine carcinomas with poor differentiation (NECs). Esophageal neuroendocrine carcinomas (NECs) are an uncommon and aggressive kind of esophageal carcinoma that mainly affects the lower oesophagus and has positive neuroendocrine immunohistochemistry markers. The most prevalent gastrointestinal symptoms of esophageal NECs are dysphagia and/or stomach pain. They have the potential to spread to other parts of the body. The current case series outlines the most recent classification of esophageal neuroendocrine neoplasms. All of the patients have dysphagia and ulcerative development patterns, as well as positive neuroendocrine immunohistochemistry markers. Author (S) Details Niti Dalal Department of Pathology, PGIMS, Rohtak, India. Sunita Singh Department of Pathology, PGIMS, Rohtak, India. View Boo...

Background: Adenocarcinomas of the prostate gland are commonly encountered globally but other uncommon variants of carcinoma of the prostate are sporadically encountered including primary sarcomatoid carcinoma of the prostate (PSCP). Aims: To review the literature of PSCP. Methods: Various internet search engines were searched for literature on PSCP. Literature Review: About 100 cases of PSCP have so far been reported. PSCP may develop de novo or may emanate following hormonal therapy or radiotherapy for adenocarcinoma of prostate; PSCP may present with LUTS, haematuria, perineal/back pain. Histology of prostate biopsy tends to show a biphasic tumour which has an adenocarcinoma component as well as a second component which is a clearly recognizable type of sarcoma component which could be angiosarcoma, chondrosarcoma, leiomyosarcoma, osteosarcoma or rhabdomyosarcoma. With regard to immunohistochemistry, the epithelial component of sarcomatoid carcinoma of prostate stains...

Background: Men are known to have prostate glands but not women. The thought of prostate gland occurring in the female genital tract in women would be petrifying to all clinicians and people who are not aware of  its biological  behavior. Ectopic prostate in the uterine cervix (EPIUC) and the female genital tract (FGT) is very rare. Aim: To review the literature on EPIUC/FGT and to document its biological behavior. Methods: Information  obtained  from  17  references,  was  used to provide the  literature  review  on EPIUC/FGT. Results: Few cases of EPIUC/FGT have been reported at ages ranging between 21 and 82 years EPIUCs/FGTs  may  be  diagnosed  incidentally  in  biopsies  of  the  cervix/vagina/vulva,  or  in hysterectomy specimens or they may mimic leiomyomas. Histological examination of cervical biopsies or  of  the  cervix...