A Comparative Study of Effects of Adding Dexmedetomidine and Fentanyl as an Adjuvant to Isobaric Levobupivacaine in Lower Segment Cesarean Section: A Prospective Randomized Double-Blind Clinical Study | Chapter 3 | New Frontiers in Medicine and Medical Research Vol. 9
Background: Intrathecal Bupivacaine is the most often used local anaesthetic for lower segment caesarean sections, but researchers are always exploring for new local anaesthetics with better safety profiles for both the mother and the foetus. Many adjuvants, such as fentanyl, morphine, or tramadol, have been used with intrathecal local anaesthetics in the past to prolong intraoperative anaesthesia and postoperative analgesia. There is no literature on the use of dexmedetomidine as an adjuvant with isobaric levobupivacaine. As a result, we wanted to see how dexmedetomidine and fentanyl performed in lower segment caesarean sections when paired with 0.5 percent isobaric intrathecal levobupivacaine in spinal anaesthesia. Methodology: Following clearance by the institutional ethical committee and informed written agreement, patients were divided into three equal groups: Group L will get 2.5 ml of 0.5 percent isobaric levobupivacaine, 5 g dexmedetomidine, and 25 g fentanyl intrathecally; G...