Determining the Effect of Injection Dexmedetomidine for Prevention of Pain due to Propofol Injection and Comparing it with Injection Lignocaine | Chapter 02 | New Horizons in Medicine and Medical Research Vol. 1
Background: Local pain after a Propofol injection is a common occurrence. Different ways have been tried to alleviate the discomfort, but they have had mixed results. The purpose of this study was to examine the efficacy of injection Dexmedetomidine 0.2 mcg/kg against injection Lignocaine 0.2 mg/kg in preventing pain caused by Propofol injection. Method: The study was started with written informed consent from the participants after receiving clearance from the Institutional Ethics Committee. In a randomised prospective trial, 60 ASA I and II patients between the ages of 20 and 60 years, of either sexe, were randomly assigned to one of two groups for elective procedures under general anaesthesia. Injection Dexmedetomidine 0.2mcg/kg in Group I (Dexmedetomidine group), and Injection Lignocaine 0.2 mg/kg in Group II (Lignocaine group). In 5 mL normal saline, both were diluted. A 20 G cannula was used to secure the IV line, and a pneumatic tourniquet was used to apply venous o...