Relevance of Brain Stem and Visual Evoked Potentials in Diagnosis of Central Demyelination in Guillain Barre Syndrome | Chapter 12 | Emerging Research in Medical Sciences Vol. 2
Aims: Guillain Barre Syndrome (GBS) is an auto-immune mediated demyelination polyradiculoneuropathy. Clinical features include progressive symmetrical ascending muscle weakness of more than two limbs, areflexia with or without sensory, autonomic and brainstem abnormalities. The purpose of this study was to determine subclinical neurological changes of CNS with GBS & to establish the presence of central demyelination in GBS. Study Design: A prospective study to find out early Central demyelination in clinically diagnosed patients of GBS. Place and Duration of Study: Department of Physiology, Pt. B.D. Sharma Post-Graduate Institute of Medical Sciences, University of Health Sciences, Rohtak, Haryana, India, between January 2014 and June 2015. Methodology: The patients were referred from the Department of Medicine to our Department for electro-diagnostic evaluation. The study group comprised of 40 subjects (20 clinically diagnosed GBS patients and 20 healthy indi...