Relationship of Apolipoprotein B-100 and Lipid Profile Parameters among Diabetic Patients in a Tertiary Hospital in Nigeria | Chapter 06 | Current Trends in Disease and Health Vol. 2
Diabetic dyslipidaemia is the bane of most complications seen in diabetes mellitus. The aim of our study is to determine the levels of apolipoprotein B-100 among diabetic adults and non-diabetic control; and its relationship with the traditional lipid profile parameters. A total of 58 subjects including 30 diabetic patients and 28 non-diabetic controls selected from diabetic clinic and immunization centres respectively. Subjects were randomly selected, examined clinically and have their anthropometric parameters measured. Lipid profile was assayed using standard enzymatic spectrophotometric methods while serum apolipoprotein B-100 was measured using sandwich immunoassay technique. Data were expressed in means and standard deviations. Differences in means between the two groups were assessed using Student T-test and relationships tested using Pearson’s correlation study. Mean ages of diabetic and non-diabetic groups were 57.7±7.4 and 49.3± 17.9 years respectively (p>0.05). Stati...