B P International

  The goal is to look at the link between a serotonin transporter gene polymorphism and state-trait anxiety, as well as to see if 5-HTTLPR may be utilised as an objective predictor of mental state in Japanese ballet dancers under stress. There were 25 elite student ballet (Elite) dancers with future promise and 19 professional ballet (Pro) dancers that took part in the competition. On a regular day and one of the stressful days, we gave the subjects two psychological questionnaires (STAI: State-Trait Anxiety Inventory; BRUMS: Brunel Mood Scale). The 5-HTTLPR genotype was found in 64.7 percent of the dancers, 35.3 percent in the s/l group, and 0 percent in the l/l group. Only the s/s and s/l genotypes had significant differences in STAI scores before competition. Elite dancers' Trait-Anxiety scores were substantially higher than those of Pro dancers in this study (P0.028). The primary impacts of genotypes on BRUMS scores (P0.035) and Pro/Elite groups (P0.002) were substantial; the 5...

Aims: To determine if whether, in a hippocampal neuron culture model subjected to nutrient deprivation stress (simulating degenerative disease state), Ashwagandha and/or two of its putative active ingredients, withanolide A or withaferin A, affect any of the following: neurite outgrowth, neuronal survival, activation of the pro-survival PI-3K/Akt and MAPK cascades, phosphorylation of CREB and expression of brain-derived neurotrophic factor (BDNF). Study Design: To primary rat embryonic hippocampal neurons in culture, half of which were subjected to nutrient deprivation stress, inhibitors of the PI-3K/Akt and MAPK cascade (LY294002 and PD98059, respectively) were applied, followed by Ashwagandha, withanolide A or withaferin A. Methodology: Neuronal survival was determined by using fluorescently labeled markers for live vs dead cells and by lactate dehydrogenase assay. Average neurite length was measured under phase-contrast microscopy. And intracellular signal transd...

Background: Congenital Heart Diseases (CHD) are defined as malformations of the heart and great vessels that develop in utero which may manifest at birth or later in childhood. They can be caused by numerous genetic and environmental factors.   Genetic factors are nonmodifiable.   However, identification   of   modifiable   environmental   risk   factors   is   important   to   develop   population   based prevention strategies to reduce the incidence of CHD. Objectives: The primary objective of the study was to find an association of the maternal lifestyles with CHD in new-borns. The secondary outcome of the study was to identify maternal factors that can be modified for the primary prevention of CHD. Materials   and   Methods: This   prospective   study   involved   cardiovascular   system   examination   of newborns after delivery in term gestations in 1...

Teaching is an emotional profession that requires delicate balances. This study aims to explore the ways in which teachers in the Eastern Galilee (Israel's northern periphery) cope with stress. Our main purpose is to examine the links between teachers’ stress, its sources and consequences, and stress management techniques and their positive or negative effect on stress. To reveal the associations between these variables, we posited four main hypotheses: 1) there is a positive   correlation   between   stress   and   the   intensity   of   negative   emotions;   2)   there   is   a   negative correlation between the level of stress and the ability to cope with it; 3) there is a negative correlation between   the   intensity   of   negative   emotions   and   the   ability   to   cope   with   stress;   and   4)   there   is ...