Ectopic Prostate in the Uterine Cervix / Female Genital Tract Including Vagina and Vulva: A Review of the Literature | Chapter 07 | Current Trends in Medicine and Medical Research Vol. 4
Background:
Men are known to have prostate glands but not women. The thought of prostate
gland occurring in the female genital tract in women would be petrifying to all
clinicians and people who are not aware of
its biological behavior. Ectopic
prostate in the uterine cervix (EPIUC) and the female genital tract (FGT) is
very rare.
Aim:
To review the literature on EPIUC/FGT and to document its biological behavior.
Methods:
Information obtained from
17 references, was
used to provide the
literature review on EPIUC/FGT.
Results:
Few cases of EPIUC/FGT have been reported at ages ranging between 21 and 82
years EPIUCs/FGTs may be
diagnosed incidentally in
biopsies of the
cervix/vagina/vulva, or in hysterectomy specimens or they may mimic
leiomyomas. Histological examination of cervical biopsies or of
the cervix in
hysterectomy specimens tends to reveal
ducts and acini
some papillary or cribriform, with
prominent squamous metaplasia EPIUCs/FGTs which does show positive Immunohisto-chemical staining
for prostate specific
antigen (PSA), prostatic-specific acid phosphatase (PSAP [PAP]), high molecular
weight keratin (for basal cells). EPIUCs reported so far have exhibited benign
behavior.
Conclusions:
Information obtained from the literature would indicate that EPIUCs / FGTs are
rare and so far have exhibited benign behavior. Clinicians should report cases
of EPIUC/FGT in order to establish whether or not EPIUCs/FGTs may or may not
develop into carcinomas in the future. Ectopic prostate in
the uterine cervix
and the female
genital tract is
very rare and
pathologists and gynaecologists may
not be familiar
with this entity
because of its
rarity. The differential
diagnoses include:
adenocarcinoma in situ,
adenoid basal carcinoma
of the cervix
and minimal deviation adenocarcinoma of the cervix. It is
important for pathologists, gynaecologists and all clinicians to be aware of
the presence of
ectopic prostate in the uterine
cervix, vagina and
vulva in order
that an accurate diagnosis is
made and in order to avoid unwarranted radical surgical treatment.
Author(s) Details
Mr Anthony Kodzo-Grey Venyo
MB ChB FRCS(Ed) FRCSI FGCS Urol. LLM
Department of Urology, North
Manchester General Hospital, Manchester, United Kingdom.
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