Skip to main content

Determination of High Sensitivity C-Reactive Protein in Metabolic Syndrome | Chapter 12 | New Frontiers in Medicine and Medical Research Vol. 5

Background: If a person has metabolic syndrome, their risk of cardiovascular disease and type 2 diabetes mellitus is greatly elevated. In India, obesity and type 2 diabetes have become epidemics. Low-grade systemic inflammation characterises metabolic syndrome, which is a pro-inflammatory disease. C-reactive protein (CRP), a biomarker, is a reliable sign of chronic systemic inflammation. Higher levels of high sensitivity C-reactive protein (Hs-crp) have been associated to metabolic syndrome and its components, and can help predict future cardiovascular events. The following are the goals of the research: 1) The link between metabolic syndrome and high-sensitivity C reactive protein 2)An investigation of high-sensitivity C reactive protein as a surrogate measure of chronic inflammation in the metabolic syndrome. Methods and Materials The participants in this cross-sectional study included 50 patients with metabolic syndrome aged 18 and up, as well as 50 age and sex matched controls who came to the OPD or were admitted to the Bangalore Medical College medical department wards. Using the new IDF criteria, metabolic syndrome was identified. A fasting blood sample was obtained to determine the levels of hs-CRP, blood glucose, and lipid profile. The waist circumference, height, and weight were all the same. The values of several demographic characteristics such as BMI, waist circumference, blood pressure, and biochemical parameters such as blood sugar and lipid profile between cases and controls were statistically significant. With a p value of 0.001, patients with metabolic syndrome had a higher mean value of hs-CRP (8.31.04 vs 1.60.79mg/l). Conclusion: Patients with metabolic syndrome had significantly higher levels of hs-CRP when compared to controls, and hs-CRP levels grew linearly with the number of metabolic syndrome components. As a result, hs-CRP can most likely be used as a surrogate marker of chronic inflammation in patients with metabolic syndrome.

Author(s) Details

Prakash Kikkeri Gowdaiah
Department of Medicine, Bangalore Medical College and Research Institute, Bangalore, India.

Dr. T. R. Mamatha
Department of Medicine, Bangalore Medical College and Research Institute, Bangalore, India.

Dyaneshwar Nirgude
Department of Medicine, Bangalore Medical College and Research Institute, Bangalore, India.
Irinel Popescu

Prakash Basappa Hosamani
Department of Medicine, Bangalore Medical College and Research Institute, Bangalore, India.


View Book :- https://stm.bookpi.org/NFMMR-V5/article/view/3028

 

Labels:

Comments

Post a Comment

Popular posts from this blog

Greening Regional Airports: A Vision for Carbon Neutral Infrastructure | Chapter 12 | Contemporary Perspective on Science, Technology and Research Vol. 3

 This study provides an overview of the energy demand of a regional airport, divided into individual time horizons. The electrification of aircraft systems raises the question of whether airports will be among the largest electricity consumers in our infrastructure in the future. Sustainability and especially emission reductions are significant challenges for airports that are currently being addressed. The Clean Sky 2 project GENESIS addresses the environmental sustainability of hybrid-electric 50-passenger aircraft systems in a life cycle perspective to support the development of a technology roadmap for the transition to sustainable and competitive electric aircraft systems. This article originates from the GENESIS research and describes various options for ground power supply at a regional airport. Potential solutions for airport infrastructure with a short (2030), medium (2040), and long (2050) time horizon are proposed. In addition to the environmental and conservation benefi...
Post a Comment
Read more

Study on Processing Method Influences the Effect of Cassava (Manihot esculenta) Consumption on Blood Lipid Profile in Rats | Chapter 8 | Current Research and Development in Chemistry Vol.1

Cassava is consumed in many tropical countries and is fast becoming the major raw material of many diets, especially in the bakery, brewery and pharmaceutical industries. In a study to determine the effects of various formulations of Cassava feeds on blood lipid profile in rats. Forty adult Wistar rats weighing between 120 and 150 g were divided into 4 groups of 10 rats each. The rats were acclimatized for one week; fed with different formulations of Cassava feeds adlibitum, after which the rats were allotted into groups. Group 1 was fed on Garri; group 2 on Cassava flour; group 3 on Tapioca, and the control group (group 4) on normal chow. After 4 weeks, each animal was anaesthetized by exposure to chloroform vapour and blood samples collected by cardiac puncture. Group 1 diet (Garri) significantly increased HDL-cholesterol (HDL-C) concentration and significantly decreased LDL-cholesterol (LDL-C) concentration (p<0.05) compared with the control group. In Group 2 (Cassava flour), t...
Post a Comment
Read more

Ethnopharmacological Survey among Traditional Medicine Practitioners in Abidjan (Côte d'Ivoire) for the Management of Pathologies such as Malaria, ENT Diseases, Diarrhea, Typhoid Fever and Anemia | Chapter 05 | New Horizons in Medicine and Medical Research Vol. 8

 Traditional Medicine Practitioners (TMPs) of Côte d'Ivoire are familiar with the therapeutic herbs. Medicinal plants have been shown to be useful in the treatment of common diseases such as malaria (KROA, 2004) and diabetes (N'GUESSAN et al, 2013) in several studies and scientific study. In the Abidjan District, the current policy is to integrate traditional medicine and pharmacopoeia into the national health system in order to improve population health coverage, particularly in the management of commonly encountered diseases such as malaria, ENT diseases, diarrhoea, typhoid fever, and anaemia. This research aims to increase the use of traditional medicine and pharmacopoeia in the national health system. Over the course of three months, fifty (50) PMTs in the District of Abidjan participated in this study. Plant therapists accounted for 30 of the 50 PMTs polled at the end of the study, or 60%. Traditional medicine centres use 61 types of medicinal plants from 36 famili...
Post a Comment
Read more