Skip to main content

Determination of High Sensitivity C-Reactive Protein in Metabolic Syndrome | Chapter 12 | New Frontiers in Medicine and Medical Research Vol. 5

Background: If a person has metabolic syndrome, their risk of cardiovascular disease and type 2 diabetes mellitus is greatly elevated. In India, obesity and type 2 diabetes have become epidemics. Low-grade systemic inflammation characterises metabolic syndrome, which is a pro-inflammatory disease. C-reactive protein (CRP), a biomarker, is a reliable sign of chronic systemic inflammation. Higher levels of high sensitivity C-reactive protein (Hs-crp) have been associated to metabolic syndrome and its components, and can help predict future cardiovascular events. The following are the goals of the research: 1) The link between metabolic syndrome and high-sensitivity C reactive protein 2)An investigation of high-sensitivity C reactive protein as a surrogate measure of chronic inflammation in the metabolic syndrome. Methods and Materials The participants in this cross-sectional study included 50 patients with metabolic syndrome aged 18 and up, as well as 50 age and sex matched controls who came to the OPD or were admitted to the Bangalore Medical College medical department wards. Using the new IDF criteria, metabolic syndrome was identified. A fasting blood sample was obtained to determine the levels of hs-CRP, blood glucose, and lipid profile. The waist circumference, height, and weight were all the same. The values of several demographic characteristics such as BMI, waist circumference, blood pressure, and biochemical parameters such as blood sugar and lipid profile between cases and controls were statistically significant. With a p value of 0.001, patients with metabolic syndrome had a higher mean value of hs-CRP (8.31.04 vs 1.60.79mg/l). Conclusion: Patients with metabolic syndrome had significantly higher levels of hs-CRP when compared to controls, and hs-CRP levels grew linearly with the number of metabolic syndrome components. As a result, hs-CRP can most likely be used as a surrogate marker of chronic inflammation in patients with metabolic syndrome.

Author(s) Details

Prakash Kikkeri Gowdaiah
Department of Medicine, Bangalore Medical College and Research Institute, Bangalore, India.

Dr. T. R. Mamatha
Department of Medicine, Bangalore Medical College and Research Institute, Bangalore, India.

Dyaneshwar Nirgude
Department of Medicine, Bangalore Medical College and Research Institute, Bangalore, India.
Irinel Popescu

Prakash Basappa Hosamani
Department of Medicine, Bangalore Medical College and Research Institute, Bangalore, India.


View Book :- https://stm.bookpi.org/NFMMR-V5/article/view/3028

 

Labels:

Comments

Post a Comment

Popular posts from this blog

Greening Regional Airports: A Vision for Carbon Neutral Infrastructure | Chapter 12 | Contemporary Perspective on Science, Technology and Research Vol. 3

 This study provides an overview of the energy demand of a regional airport, divided into individual time horizons. The electrification of aircraft systems raises the question of whether airports will be among the largest electricity consumers in our infrastructure in the future. Sustainability and especially emission reductions are significant challenges for airports that are currently being addressed. The Clean Sky 2 project GENESIS addresses the environmental sustainability of hybrid-electric 50-passenger aircraft systems in a life cycle perspective to support the development of a technology roadmap for the transition to sustainable and competitive electric aircraft systems. This article originates from the GENESIS research and describes various options for ground power supply at a regional airport. Potential solutions for airport infrastructure with a short (2030), medium (2040), and long (2050) time horizon are proposed. In addition to the environmental and conservation benefi...
Post a Comment
Read more

Alkali Element Modification of Glucose Molecules as a Method to Dissolve Cancer Cells | Chapter 12 | New Visions in Medicine and Medical Science Vol. 4

  The present study highlights about alkali element modification of glucose molecules as a method to dissolve cancer cells. The central regulation of the mechanisms governing cell proliferation has little effect on cancer cells. Cancer cells are entirely independent of the central command and divide and proliferate on their own, making it challenging to activate their response mechanism. Precisely, this is the reason why they are at risk to the health of humans and/or any biological entities. Instead of trying to reconnect the central command of the growth control mechanism to cancer cells that are already out of the range, we present a method of using the cancer cell’s own irresponsive and uncontrolled growth mechanism to their disadvantage and destroy the cancer cells. We found that this is achievable in an atomic/molecular level study of the glucose molecule, which is the primary food source used for growth and energy generation by all cells in the body, including the cancer cel...
Post a Comment
Read more

Diagnosis and Management of Scrapie in Post Mortem Goats by Immunohistochemistry | Chapter 6 | New Visions in Medicine and Medical Science Vol. 4

  The main objective of this study was to contribute to the annual passive surveillance for this pathology, since the goats are a species considered reservoir for the prion. A class of pathologies known as Transmissible Spongiform Illnesses (TSEs), which affect both humans and animals, includes scrapie, a neurological disease with a slow and deadly course that affects sheep, goats, and mouflons. Given that Immunohistochemistry (IHC) is the globally accepted technique for identifying classical scrapie in goats—a species thought to be a potential zoonotic disease reservoir. Chile in relation to Bovine Spongiform Encephalopathy (BSE), is classified as a disease-free country. Scrapie is actively monitored for the sheep, but passively for the caprine species, which is why this study was carried out in slaughtered goats in the central north of the country (IV Region), to provide information to the surveillance system for this disease. Fifty brains of goats older than 2 years were used, r...
Post a Comment
Read more