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An Unusual Case Presentation on Giant Non-Functioning Adrenocortical Carcinoma | Chapter 21 | New Horizons in Medicine and Medical Research Vol. 1

 A case of gigantic non-functioning adrenocortical carcinoma without pressure effects is shown here, which is a rare occurrence. Adrenocortical carcinoma is an uncommon tumour with a global incidence of 1 per million. The age distribution is bimodal, with maxima at 5-20 and 40-50 years old. Tumors that are larger than 9 cm frequently affect the inferior vena cava (IVC) or the right side of the heart. The carcinomas are functioning in 80% of cases. We present a case of a rare non-functioning adrenocortical carcinoma in a 40-year-old woman with an incidence of 0.5/million worldwide, no extra-adrenal dissemination at presentation, and no IVC or right ventricular involvement despite a tumour size of 12 cm. With regular follow-ups and disease-free life following the surgery, the patient had a successful surgical extirpation with adjuvant radiotherapy. Hormone levels in symptomatic and asymptomatic patients with adrenal masses must be determined. The possibility of adrenocortical carcinoma should not be ruled out in either a functioning or non-functioning tumour. On computed tomography (CT)/magnetic resonance imaging (MRI), all solid incidentalomas larger than 5 cm should be surgically removed, with adjuvant therapy recommended after histological examination.


Author(S) Details

Abhishek R. Potnis
Department of Surgery, Government Medical College and Cancer Hospital, Aurangabad, Maharashtra, India.

Ajay K. Boralkar
Department of Surgery, Government Medical College and Cancer Hospital, Aurangabad, Maharashtra, India.

Abdul Rafe
Department of Surgery, Government Medical College and Cancer Hospital, Aurangabad, Maharashtra, India.

Sarojini P. Jadhav
Department of Surgery, Government Medical College and Cancer Hospital, Aurangabad, Maharashtra, India.

View Book:- https://stm.bookpi.org/NHMMR-V1/article/view/6186

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