The main objective of this study was to contribute to the annual passive surveillance for this pathology, since the goats are a species considered reservoir for the prion. A class of pathologies known as Transmissible Spongiform Illnesses (TSEs), which affect both humans and animals, includes scrapie, a neurological disease with a slow and deadly course that affects sheep, goats, and mouflons. Given that Immunohistochemistry (IHC) is the globally accepted technique for identifying classical scrapie in goats—a species thought to be a potential zoonotic disease reservoir. Chile in relation to Bovine Spongiform Encephalopathy (BSE), is classified as a disease-free country. Scrapie is actively monitored for the sheep, but passively for the caprine species, which is why this study was carried out in slaughtered goats in the central north of the country (IV Region), to provide information to the surveillance system for this disease. Fifty brains of goats older than 2 years were used, r...
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