Skip to main content

Intestinal Tuberculosis in Surgical Pathology | Chapter 08 | Current Trends in Disease and Health Vol. 1

Background: Intestinal tuberculosis (ITB) represents the most common type of abdominal TB. Definitive diagnosis of intestinal tuberculosis is made on the basis of morphological examination of surgical specimens in majority of cases as clinico-radiological features are non-specific in initial stages of the disease.


Aims: To analyze the surgical pathology data on intestinal tuberculosis of the hospital and to document findings of morphological examination.

Setting: A descriptive study of intestinal tuberculous lesions encountered in surgical specimens received during a period of three years in the histopathology section of a tertiary care hospital.

Materials and Methods: 40 cases of intestinal tuberculosis out of 250 consecutive, surgically excised specimens of small and large bowel were included in this study. One year retrospective and two years prospective data is included in the study.

Results: Intestinal obstruction was the most frequent clinical presentation followed by perforation peritonitis in ITB cases in this series.9 patients had past history of pulmonary and/or intestinal tuberculosis. Out of 31patients without past history of TB, 25.80% were suspected of having TB preoperatively on the basis of clinical and imaging findings. Ileal and ileo-caecal region was most frequently involved. The three gross morphological forms of tuberculous enteritis seen were ulcerative in 82.5%, ulcero-hypertrophic in 15% and hypertrophic in 2.5% cases. Characteristic caseating granulomas were seen in 60% cases.

Conclusion: Changes in clinical presentation of Intestinal TB are being observed. High index of suspicion is needed at every step of diagnosis of intestinal TB as many non-tuberculous lesions share same clinical and radiological findings.

Author(s) Details

Dr. Sandhya V. Poflee
Department of Pathology, Government Medical College and Hospital, Nagpur, Maharashtra, India.

Dr. Balaji D. Baste, MBBS, MD Pathology
Department of Pathology, Seth GSMC and KEM Hospital, Mumbai, Maharashtra, India.

Dr. Radha P. Munje, MBBS, DTCD, MD (Med)
Department of Pulmonary Medicine, Indira Gandhi Government Medical College and Hospital, Nagpur, Maharashtra, India.

Read full article: http://bp.bookpi.org/index.php/bpi/catalog/view/59/647/527-1
View Volume: https://doi.org/10.9734/bpi/ctdah/v1
Labels:

Comments

Post a Comment

Popular posts from this blog

Greening Regional Airports: A Vision for Carbon Neutral Infrastructure | Chapter 12 | Contemporary Perspective on Science, Technology and Research Vol. 3

 This study provides an overview of the energy demand of a regional airport, divided into individual time horizons. The electrification of aircraft systems raises the question of whether airports will be among the largest electricity consumers in our infrastructure in the future. Sustainability and especially emission reductions are significant challenges for airports that are currently being addressed. The Clean Sky 2 project GENESIS addresses the environmental sustainability of hybrid-electric 50-passenger aircraft systems in a life cycle perspective to support the development of a technology roadmap for the transition to sustainable and competitive electric aircraft systems. This article originates from the GENESIS research and describes various options for ground power supply at a regional airport. Potential solutions for airport infrastructure with a short (2030), medium (2040), and long (2050) time horizon are proposed. In addition to the environmental and conservation benefi...
Post a Comment
Read more

Occipital Dermal Sinus Tract Causing Craniospinal Infection: A Review | Chapter 13 | New Visions in Medicine and Medical Science Vol. 4

  Dermal sinus is a rare congenital condition characterized by a pathological tract connecting the skin to deeper tissues of the central nervous system, potentially leading to severe infectious complications. It arises from a failure in the separation of ectodermal layers during early gestation. Diagnosing dermal sinus tract in newborns requires a careful physical examination, focusing on midline dimples in the occipital region associated with cutaneous abnormalities like hairy nevus or hyperpigmentation. The presence of drainage, abnormal hair distribution, or localized swelling may indicate a sinus tract. Regular examination for dimples or sinuses is recommended for infants and children with recurrent meningitis or infections. Early detection is crucial to prevent severe complications like meningitis, with Staphylococcus aureus being a common causative organism. Neuroradiological studies, including computed tomography (CT) scan and magnetic resonance imaging (MRI), with histopath...
Post a Comment
Read more

Alkali Element Modification of Glucose Molecules as a Method to Dissolve Cancer Cells | Chapter 12 | New Visions in Medicine and Medical Science Vol. 4

  The present study highlights about alkali element modification of glucose molecules as a method to dissolve cancer cells. The central regulation of the mechanisms governing cell proliferation has little effect on cancer cells. Cancer cells are entirely independent of the central command and divide and proliferate on their own, making it challenging to activate their response mechanism. Precisely, this is the reason why they are at risk to the health of humans and/or any biological entities. Instead of trying to reconnect the central command of the growth control mechanism to cancer cells that are already out of the range, we present a method of using the cancer cell’s own irresponsive and uncontrolled growth mechanism to their disadvantage and destroy the cancer cells. We found that this is achievable in an atomic/molecular level study of the glucose molecule, which is the primary food source used for growth and energy generation by all cells in the body, including the cancer cel...
Post a Comment
Read more