Skip to main content

Computational Analysis of Evolutionary Relationship of a Family of Cold Shock Proteins in Ten Mammalian Species | Chapter 11 | Advances and Trends in Biotechnology and Genetics Vol. 2

Aims: This study was carried out to evaluate the evolutionary relationship of a family of cold shock proteins (CSP) in ten mammalian species using bioinformatics tools and softwares such as Genbank, FASTA, BLAST and MEGA 5.

Sample: Twenty protein sequences of both RBM3 and CIRP proteins of some selected mammalian species were downloaded from NCBI database.

Study Design: Computational analysis to evaluate the evolutionary relationship of the CSP was carried out by estimating the phylogenic relationship of CSP in the different mammalian species studied.

Place and Duration of Study: This study was carried out at the Department of Genetics and Biotechnology, Calabar.

Methodology: The molecular evolution and genetic analysis, version 5 (MEGA 5) software was used to determine the evolutionary relationship of both CIRP and RBM3 in the ten mammalian species studied by constructing phylogenic tree using the amino acid sequences of protein retrieved from NCBI.

Results: The highest identity (100%) was observed between Ovis aries and Bos Taurus; Rattus norvegicus and Mus-musculus while the least percentage identity was observed between Pan troglodytes and Bos taurus (84%). The phylogenic relationship using UPGMA based on Jones-Taylor-Thornton (JTT) matrix model revealed high relationship.

Conclusion: It was observed that evolutionary relationship of CIRP and RBM3 revealed high relatedness among the mammalian species studied.

Author(s) Details

E. A. Okon
Department of Biological Science, Cross River University of Technology, Calabar, Nigeria.

E. V. Ikpeme
Department of Genetics and Biotechnology, University of Calabar, Calabar, Nigeria.

O. U. Udensi
Department of Genetics and Biotechnology, University of Calabar, Calabar, Nigeria.

E. E. Ekerette
Department of Genetics and Biotechnology, University of Calabar, Calabar, Nigeria.

H. E. Etta
Department of Biological Science, Cross River University of Technology, Calabar, Nigeria.

E. P. Willie
Department of Genetics and Biotechnology, University of Calabar, Calabar, Nigeria.

M. Ozoje
Department of Genetics and Biotechnology, University of Calabar, Calabar, Nigeria.

Read full article: http://bp.bookpi.org/index.php/bpi/catalog/view/82/1172/815-1
View Volume: https://doi.org/10.9734/bpi/atbg/v2
Labels:

Comments

Post a Comment

Popular posts from this blog

Greening Regional Airports: A Vision for Carbon Neutral Infrastructure | Chapter 12 | Contemporary Perspective on Science, Technology and Research Vol. 3

 This study provides an overview of the energy demand of a regional airport, divided into individual time horizons. The electrification of aircraft systems raises the question of whether airports will be among the largest electricity consumers in our infrastructure in the future. Sustainability and especially emission reductions are significant challenges for airports that are currently being addressed. The Clean Sky 2 project GENESIS addresses the environmental sustainability of hybrid-electric 50-passenger aircraft systems in a life cycle perspective to support the development of a technology roadmap for the transition to sustainable and competitive electric aircraft systems. This article originates from the GENESIS research and describes various options for ground power supply at a regional airport. Potential solutions for airport infrastructure with a short (2030), medium (2040), and long (2050) time horizon are proposed. In addition to the environmental and conservation benefi...
Post a Comment
Read more

There is No Standard Model of ZFC and ZFC2 | Chapter 03 | Advances in Mathematics and Computer Science Vol. 1

In this Chapter we obtain a contradictions in formal set theories under assumption that these theories have omega-models or nonstandard model with standard part. An possible generalization of Lob’s theorem is considered. Main results are: (i) ¬Con(ZF C+ ∃ M ZFC st ), (ii) ¬Con(N F+ ∃ M NF st ), (iii) ¬Con(ZF C 2 ), (iv) let k be an inaccessible cardinal then ¬Con(ZF C+ ∃ κ), (v) ¬Con(ZF C+ (V=L)), (vi) ¬Con(ZF+ (V=L)). Author   Details: Jaykov Foukzon Israel Institute of Technology, Haifa, Israel Men'kova Elena Romanovna All-Russian Research Institute for Optical and Physical Measurements, Moscow, Russia Read full article: http://bp.bookpi.org/index.php/bpi/catalog/view/46/221/408-1 View Volume: https://doi.org/10.9734/bpi/amacs/v1
Post a Comment
Read more

Study on Processing Method Influences the Effect of Cassava (Manihot esculenta) Consumption on Blood Lipid Profile in Rats | Chapter 8 | Current Research and Development in Chemistry Vol.1

Cassava is consumed in many tropical countries and is fast becoming the major raw material of many diets, especially in the bakery, brewery and pharmaceutical industries. In a study to determine the effects of various formulations of Cassava feeds on blood lipid profile in rats. Forty adult Wistar rats weighing between 120 and 150 g were divided into 4 groups of 10 rats each. The rats were acclimatized for one week; fed with different formulations of Cassava feeds adlibitum, after which the rats were allotted into groups. Group 1 was fed on Garri; group 2 on Cassava flour; group 3 on Tapioca, and the control group (group 4) on normal chow. After 4 weeks, each animal was anaesthetized by exposure to chloroform vapour and blood samples collected by cardiac puncture. Group 1 diet (Garri) significantly increased HDL-cholesterol (HDL-C) concentration and significantly decreased LDL-cholesterol (LDL-C) concentration (p<0.05) compared with the control group. In Group 2 (Cassava flour), t...
Post a Comment
Read more