Skip to main content

Computational Analysis of Evolutionary Relationship of a Family of Cold Shock Proteins in Ten Mammalian Species | Chapter 11 | Advances and Trends in Biotechnology and Genetics Vol. 2

Aims: This study was carried out to evaluate the evolutionary relationship of a family of cold shock proteins (CSP) in ten mammalian species using bioinformatics tools and softwares such as Genbank, FASTA, BLAST and MEGA 5.

Sample: Twenty protein sequences of both RBM3 and CIRP proteins of some selected mammalian species were downloaded from NCBI database.

Study Design: Computational analysis to evaluate the evolutionary relationship of the CSP was carried out by estimating the phylogenic relationship of CSP in the different mammalian species studied.

Place and Duration of Study: This study was carried out at the Department of Genetics and Biotechnology, Calabar.

Methodology: The molecular evolution and genetic analysis, version 5 (MEGA 5) software was used to determine the evolutionary relationship of both CIRP and RBM3 in the ten mammalian species studied by constructing phylogenic tree using the amino acid sequences of protein retrieved from NCBI.

Results: The highest identity (100%) was observed between Ovis aries and Bos Taurus; Rattus norvegicus and Mus-musculus while the least percentage identity was observed between Pan troglodytes and Bos taurus (84%). The phylogenic relationship using UPGMA based on Jones-Taylor-Thornton (JTT) matrix model revealed high relationship.

Conclusion: It was observed that evolutionary relationship of CIRP and RBM3 revealed high relatedness among the mammalian species studied.

Author(s) Details

E. A. Okon
Department of Biological Science, Cross River University of Technology, Calabar, Nigeria.

E. V. Ikpeme
Department of Genetics and Biotechnology, University of Calabar, Calabar, Nigeria.

O. U. Udensi
Department of Genetics and Biotechnology, University of Calabar, Calabar, Nigeria.

E. E. Ekerette
Department of Genetics and Biotechnology, University of Calabar, Calabar, Nigeria.

H. E. Etta
Department of Biological Science, Cross River University of Technology, Calabar, Nigeria.

E. P. Willie
Department of Genetics and Biotechnology, University of Calabar, Calabar, Nigeria.

M. Ozoje
Department of Genetics and Biotechnology, University of Calabar, Calabar, Nigeria.

View Volume: https://doi.org/10.9734/bpi/atbg/v2

Comments

Popular posts from this blog

Consensus Summit: Lipids and Cardiovascular Health in the Nigerian Population | Chapter 09 | Current Trends in Food Science Vol. 1

Aims: To issue a consensus statement on Lipids and Cardiovascular Health and the impact of their interrelationship in Nigerian Population. Study Design: Experts from a range of relevant disciplines, deliberated on different aspects of Lipids and Cardiovascular Health in the Nigerian Population at a Summit. Place and Duration of Study: The Summit was held in April 2016 at the Nigerian Institute of Medical Research. Methodology: Presentations were made on central themes after which expert participants split into four different groups to consider the questions relevant to different sub themes of the title. Consensus was arrived at, from presentations of groups at plenary. Conclusion: With the increase in the prevalence of NCDs, especially Cardiovascular Disease in Nigeria, and the documented evidence of deleterious effects of lipids, the expert panel called for an urgent need to advocate for the general public and health professionals to make heart-friendly

A Review on Gongronema latifolium, an Extremely Useful Plant with Great Prospects | Chapter 11 | Recent Advances in Biological Research Vol. 3

Gongronema latifolium is a plant that has a wide range of nutritional and ethnomedical uses in different tropical African communities. Scientific reports on the chemical composition and bioactivity (anti-inflammatory, antimicrobial, antidiabetic, antioxidant, anticancer and allelopathic properties) of the plant material by different authors are discussed in this review. Future prospects of the plant extracts in the areas of herbal formulations, food preservation, alcoholic fermentation and beer production, drug discovery and allelopathy are also highlighted. Author   Details: Olugbenga Morebise Faculty of Basic Medical Sciences, All Saints University School of Medicine, Roseau, Commonwealth of Dominica. Read full article: http://bp.bookpi.org/index.php/bpi/catalog/view/50/403/433-1 View Volume: https://doi.org/10.9734/bpi/rabr/v3

Dictionary of Medicinal Plants - Scientific Names, Family and Selected Vernacular (English, Sinhala, Sanskrit and Tamil) Names | Book Publisher International

Medicinal plants have been known for centuries and are highly valued all over the world as a rich source of therapeutic agents of medicinal plants for public health care in developing nations [65]. Even today, the WHO estimates that up to 80 percent of the world population still relies mainly on traditional remedies such as herbs for their primary health care [13]. Ahmed et al. mentioned that according to a survey conducted by W.H.O., traditional healers treat 65% patients in Sri Lanka and 80% in India [3]. According to the WHO, around 21,000 plant species have the potential for being used as medicinal plants. Different ethnic and different language speaking peoples are living in Asian countries. Plants are commonly known by their local names in every part of the world. These local names play a very important role in ethno-botanical study of a specific tribe or region. Local names given to plants by indigenous people in their local dialects often reflect a broad spectrum of inf