Skip to main content

Spectrum of Thyroid Diseases in Makurdi, Benue State of Nigeria: A Review of 94 Consecutive Cases | Chapter 09 | Modern Advances in Pharmaceutical Research Vol. 2

This study aims to review the spectrum of thyroid diseases in Makurdi, Benue State of Nigeria through a histopathological survey. It is a retrospective study covering 1st January, 2005 to 31st December, 2016.

Ninety four (94) consecutive cases of thyroidectomy specimens collected from Holy Trinity Specialist Hospital, Makurdi, Nigeria a private hospital and Benue State University Teaching Hospital, Makurdi, Nigeria between January 1st, 2005 to December 31st, 2016 were examined histologically and analyzed with regards to age and sex.

There were 7 male specimens as against 87 female specimens giving a male: female ratio of 1:12.43. Nodular colloid goiter was the commonest histological lesion accounting for 72%, followed by thyroid carcinoma which accounted for 11.66%, adenoma 10.60%. Thyroiditis, 5.30% was the fourth commonest pathology and thyroglossal cyst/duct accounted for 1.06%. Follicular carcinoma was the commonest malignancy seen accounting for 7.51% of all specimens and most occurred in females. However, most of these thyroid malignancies occurred in younger age groups (20-49years) compared to other studies in Nigeria and Africa. There is need for a large scale study in Makurdi on the relatively younger age of our thyroid malignancies, higher incidence of follicular carcinoma when compared to other African studies and the relatively high incident of thyroiditis found in this study.

Author(s) Details

B. A. Eke
Department of Surgery, College of Health Sciences, Benue State University, Makurdi, Benue State, Nigeria.

B. A. Ojo
Department of Anatomic Pathology, College of Health Sciences, Benue State University, Makurdi, Benue State, Nigeria.

A. Adekwu
Department of Surgery, College of Health Sciences, Benue State University, Makurdi, Benue State, Nigeria.

M. Efu
Department of Anaesthesia, College of Health Science, Benue State University, Makurdi, Benue State, Nigeria.

E. I. Ogwuche
Department of Surgery, College of Health Sciences, Benue State University, Makurdi, Benue State, Nigeria.

P. Abayol
Department of Surgery, Federal Medical Center, Makurdi, Benue State, Nigeria.

View Volume: https://doi.org/10.9734/bpi/mapr/v2

Comments

Popular posts from this blog

A Prospective Study about Safety and Efficacy of Perioperative Lidocaine Infusion | Chapter 09 | New Horizons in Medicine and Medical Research Vol. 8

 Opioids cause clinically significant side effects such as respiratory depression, immunosuppression, muscle rigidity, negative inotropism, nausea, vomiting, hyperalgesia, urine retention, postoperative ileus, and drowsiness. Perioperative opioids are a major contributor to the United States' and other countries' opioid epidemics. Non-opioid analgesics, particularly lidocaine, are becoming more common for perioperative use as a result of this. A total of 185 adult patients were randomly assigned to one of two groups: control group I (105 patients) [fentanyl group] or group ii (80 patients) [opioid-free anaesthesia group]. Lidocaine 1.5 mg/kg bolus followed by 1.5 mg/kg/h infusion intraoperatively, and 1.5-2 mg/kg/h infusion for 2-8 hours postoperatively were given to patients in both groups at anaesthetic induction. Intraoperatively, both groups received analgesic adjuvants such as diclofenac 75 mg, paracetamol 1 gm, and mgso4 30-50 mg/kg. If the mean arterial pressure (map)

A Brief Study of Middleware Technologies: Programming Applications and Management Systems | Chapter 15 | Novel Research Aspects in Mathematical and Computer Science Vol. 1

  Many platforms, services, applications, hardware, and operating systems are connected through the middleware layer. Because the middleware layer abstracts much low-level complexity and makes applications and software systems portable, it allows disparate systems to interface and function together in harmony. Middleware technologies enable software engineers to swiftly construct software systems and applications, allowing developers to focus on more important tasks. This chapter examines several types of middleware systems and discusses middleware capabilities, middleware operation, middleware's function in cloud-based systems, and the best middleware platforms to use. Middleware systems are widely utilised and can be found in practically any software system or application. Middleware programmes provide as a link between many sorts of systems and protocols. They serve as a mechanism for various systems. To successfully exchange information, it runs on a variety of operating system

Patients’ Perspective of Acute Post-operative Pain Management: A Multicentre Survey of Tertiary Hospitals in Maharashtra, India | Chapter 08 | New Horizons in Medicine and Medical Research Vol. 8

 When postoperative pain is adequately controlled, patients' satisfaction and patient-related outcomes (PROs) increase. Understanding the patients' perspective is crucial since it supports in the formulation of improvement strategies. Because wrong attitudes and assumptions might block pain alleviation, patients' attitudes and beliefs are critical. As a result, a multicenter study of patients' attitudes, beliefs, experiences, and satisfaction levels with acute postoperative pain management was done in Maharashtra's tertiary hospitals. In addition, the responses were examined to evaluate if the Acute Pain Service (APS) resulted in improved patient outcomes and satisfaction. A 13-item questionnaire adapted from previous studies was used to capture patients' experiences with postoperative pain treatment. The responses of 179 patients are included in the study. The findings revealed that 91.6 percent of patients experienced postoperative pain, with 75.5 percent