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Atypical Manifestation in Infection by Methicillin-Resistant Staphylococcus aureus Carrier SCCmec IV and Panton-Valentine Leukocidin-Producer in Experimental Sepsis Model | Chapter 08 | Theory and Applications of Microbiology and Biotechnology Vol. 1

Staphylococcus aureus is considered an infectious agent of great clinical importance, responsible for many different types of infection. Strains of methicillin-resistant Staphylococcus aureus (MRSA), Panton-valentine leukocidin producers, are considered more invasive, presenting clinical sequelae related to abscesses and infection in skin and soft tissues. The use of invasive techniques in hospital environment, such as the introduction of intravascular catheter in immunocompromised patients, has contributed to this microorganism spreading through the bloodstream, causing bacteremia, necrotizing pneumonia and increasing the number of septic patients in intensive care units with high mortality. In this report, atypical infections in Swiss mice using experimental model of sepsis was presented.

Author(s) Details

Giorgio Silva-Santana
Department of Pathology, School of Medicine, Fluminense Federal University, Rio de Janeiro, Brazil and Laboratory Academic Rodolfo Albino, Fluminense Federal University, Rio de Janeiro, Brazil.

Kátia C. Lenzi-Almeida
Department of Pathology, School of Medicine, Fluminense Federal University, Rio de Janeiro, Brazil and  Environmental Science and Conservation Department, School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

Vânia G. S. Lopes
Department of Pathology, School of Medicine, Fluminense Federal University, Rio de Janeiro, Brazil.

Fábio Aguiar-Alves
Department of Pathology, School of Medicine, Fluminense Federal University, Rio de Janeiro, Brazil and Laboratory Academic Rodolfo Albino, Fluminense Federal University, Rio de Janeiro, Brazil.

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