Haemostatic Disorders in Sickle Cell Disease Subjects in Nigeria: A Review of Literature | Chapter 02 | Emerging Research in Medical Sciences Vol. 2
Background:
Sickle cell disease (SCD) is an autosomal recessive disorder that is
characterised with chronic anaemia and painful crisis. SCD is associated with
hypercoagulability or prothrombotic state that can predispose to thromboembolic
complications with increasing morbidity and mortality.
Aim:
This study aimed to show the various documented haemostatic disorders and
possible thromboembolic complications among SCD subjects in Nigeria.
Methods:
A comprehensive literature search was performed using the internet search
engines linked to academic databases including Pubmed, Google Scholar, Ebsco, Hinari,
Scopus, etc. Studies involving hemostatic disorders in Nigeria were thoroughly
searched, and the references of such articles were also searched for any
probable relevant information.
Findings
and Conclusion: There is a paucity of information on
this subject in Nigeria, and there are inconsistencies in the available
studies.
Haemostatic disorders in sickle cell
disease are conditions that are associated with increased mortality and
morbidity. Further research on the level of natural anticoagulant is required
to verify the correlation between haemostatic disorders and thromboembolic
complications in SCD subjects in Nigeria
Author(s) Details
Dr. Kingsley Akaba (MBBch,
FMCPath)
Department of Haematology
and Blood Transfusion, University of Calabar Teaching Hospital, Calabar,
Nigeria.
Dr. Marcus Inyama
Department of Haematology
and Blood Transfusion, University of Calabar Teaching Hospital, Calabar,
Nigeria.
Dr. Timothy Ekwere
Department of Haematology
and Blood Transfusion, University of Uyo Teaching Hospital, Uyo, Nigeria.
Dr. Obinna Iheanacho
Department of Haematology
and Blood Transfusion, University of Calabar Teaching Hospital, Calabar,
Nigeria.
Dr. Ekpeyong Bassey
Department of Haematology
and Blood Transfusion, University of Calabar Teaching Hospital, Calabar,
Nigeria.
Ushie Godwin
Department of Haematology
and Blood Transfusion, University of Calabar Teaching Hospital, Calabar,
Nigeria.
Dr. Hogan Archibong
Department of Haematology
and Blood Transfusion, University of Calabar Teaching Hospital, Calabar,
Nigeria.
Efiok Efiok
Department of Haematology
and Blood Transfusion, University of Calabar Teaching Hospital, Calabar,
Nigeria.
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