Prevalence of Urinary Tract Infection and Antibiotic Resistance Pattern in Pregnant Women, Najran Region, Saudi Arabia | Chapter 13 | Theory and Applications of Microbiology and Biotechnology Vol. 1
Urinary Tract Infection (UTI) is one of
the commonest infectious disease in pregnancy, and in pregnancy we have very
limited number of antibiotics to treat the UTI. This study was conducted on 151
patients who attended the gynecology clinic during the study period. Nineteen
UTI proven cases of UTI were studied for prevalence of microorganism and
sensitivity pattern against different antibiotics. Among the bacteria isolated,
Escherichia coli (73.68%) and Staphylococcus aureus (10.52%) were the most
prevalent Gram negative and Gram positive bacteria respectively. To know the
resistance pattern of microorganism we used commercially available discs of
different antibiotics. Gram negative bacteria showed more resistance as
compared to Gram positive one. It is observed that the most effective
antibiotic for Gram negative isolates is Ceftriaxone (87.5%), followed by
Amoxicillin + Clavulanic acid (81.25%), Amikacin (75%), Cefuroxime (75%),
Cefixime (68.75%) and Mezlocillin (62.5%). For the Gram positive bacteria, Ceftriaxone,
Amikacin and Amoxicillin + Clavulanic acid were the most effective
antimicrobials (100%). Multidrug resistance Gram negative bacteria were also
tested for Extended-spectrum Beta Lactamase (ESBL), 35.71% of E. coli isolates
were ESBL producer.
Author(s) Details
Dr. Ali Mohamed Alshabi
Department of Clinical
Pharmacy, College of Pharmacy, Najran University, Najran, Saudi Arabia.
Dr. Majed Saeed Alshahrani
Department of Obstetics and Gyneocology, Faculty of
Medicine, Najran University, Najran, Saudi Arabia.
Dr. Saad Ahmed Alkahtani
Department of Clinical
Pharmacy, College of Pharmacy, Najran University, Najran, Saudi Arabia.
Mohammad Shabib Akhtar
Department of Clinical
Pharmacy, College of Pharmacy, Najran University, Najran, Saudi Arabia.
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