Skip to main content

Haematological Indices and Absolute CD4 Counts of Apparently Healthy Population in Ondo State, Nigeria | Chapter 08 | New Insights into Disease and Pathogen Research Vol. 3

Aims: This study was designed and conducted to establish the normal values of various haematological indices and CD4 absolute count for apparently healthy adult in Ondo State, and to compare these values with those obtained for other populations in both tropical and western countries.

Study Design:
Cross sectional study.

Place and Duration of Study:
Department of Haematology and the global HIV/AIDS Initiative Nigeria (GHAIN), Federal Medical Centre (FMC), Owo. Nigeria between July 2013 and June 2014.

Methodology:
Haematological indices and absolute CD4 count were determined in four hundred and eighty one (481) apparently healthy individuals whose ages ranged between 20–50 years, were randomly recruited into this study from the Haematology department, Federal Medical Centre, Owo.

Results:
The mean blood levels of HCT, RBC, HB and MONO were significantly lower in female subjects compared with male subjects. Also, the mean blood levels of HCT, RBC and HGB were significantly lower while the mean blood level of Retics and ESR were significantly higher with decrease in age group. The comparative values for males and females in this study were also compared with previous established baseline values in Nigeria, Kenya and US.

Conclusion:
This study was able to establish normal reference values for hematological indices and CD4 counts in apparently normal adults in Ondo State, Nigeria. This range could be useful as a basis for making some clinical decisions and also in enrolling HIV patients into the ART program when absolute CD4 counts are considered.

Author(s) Details

Bolaji David Akinbo
Department of Medical Laboratory Science, Achievers University, Owo, Ondo State, Nigeria.

Adedeji David Atere
Department of Medical Laboratory Science, Achievers University, Owo, Ondo State, Nigeria.

Hammed Bankole Fatunade
Department of Haematology, Blood Transfusion and Serology, Federal Medical Centre, Owo, Ondo State, Nigeria.

Nelson Osakpamwan Iyabor
Department of Accident and Emergency, Federal Medical Centre, Keffi, Nasarawa State, Nigeria.

Comments

Popular posts from this blog

Greening Regional Airports: A Vision for Carbon Neutral Infrastructure | Chapter 12 | Contemporary Perspective on Science, Technology and Research Vol. 3

 This study provides an overview of the energy demand of a regional airport, divided into individual time horizons. The electrification of aircraft systems raises the question of whether airports will be among the largest electricity consumers in our infrastructure in the future. Sustainability and especially emission reductions are significant challenges for airports that are currently being addressed. The Clean Sky 2 project GENESIS addresses the environmental sustainability of hybrid-electric 50-passenger aircraft systems in a life cycle perspective to support the development of a technology roadmap for the transition to sustainable and competitive electric aircraft systems. This article originates from the GENESIS research and describes various options for ground power supply at a regional airport. Potential solutions for airport infrastructure with a short (2030), medium (2040), and long (2050) time horizon are proposed. In addition to the environmental and conservation benefi...

Alkali Element Modification of Glucose Molecules as a Method to Dissolve Cancer Cells | Chapter 12 | New Visions in Medicine and Medical Science Vol. 4

  The present study highlights about alkali element modification of glucose molecules as a method to dissolve cancer cells. The central regulation of the mechanisms governing cell proliferation has little effect on cancer cells. Cancer cells are entirely independent of the central command and divide and proliferate on their own, making it challenging to activate their response mechanism. Precisely, this is the reason why they are at risk to the health of humans and/or any biological entities. Instead of trying to reconnect the central command of the growth control mechanism to cancer cells that are already out of the range, we present a method of using the cancer cell’s own irresponsive and uncontrolled growth mechanism to their disadvantage and destroy the cancer cells. We found that this is achievable in an atomic/molecular level study of the glucose molecule, which is the primary food source used for growth and energy generation by all cells in the body, including the cancer cel...

Risk Factors for Postpartum Psychiatric Disorders. A Review of the Literature | Chapter 8 | New Visions in Medicine and Medical Science Vol. 4

  Objective: The aim of this study was to explore the risk factors for the development of postpartum psychiatric disorders through international literature. Materials and Methods: Throughout many articles in PubMed, Google scholar and PsycInfo, a great amount of recent data was gathered to identify the disorders that are most common as well as their risk factors. Results: After childbirth, most commonly women experience postpartum depression, anxiety disorders, post-traumatic stress disorder and postpartum psychosis. All the disorders have many similar risk-factors with the main one being preexisting psychiatric disorder and many similar symptoms too. Conclusions: Women after childbirth are at risk of experience many psychiatric disorders, such as postpartum distress, postpartum post traumatic stress disorder and even more rarely postpartum psychosis. It is important to provide comprehensive support to ensure the well-being of both the mother and the infant and this will b...