Skip to main content

Linezolid and Methicillin Resistances in S. Aureus Isolated from the Anterior Nares of Apparently Healthy Undergraduates of the Niger Delta University, Nigeria | Chapter 03 | Theory and Applications of Microbiology and Biotechnology Vol. 2

Background: The carriage of Staphylococcus aureus in the anterior nares of subjects in the study environment has not been carried out before and this study is thus a reference study against which future studies can be compared. The isolates obtained were also tested against frequently used antibiotics as well as linezolid, an antibiotic which is of considerable importance in the treatment of Methicillin Resistant Staphylococcus aureus (MRSA).

Methods: A total of 400 nasal swabs were collected from anterior nares of apparently healthy subjects aseptically using a sterile swab sticks. The antibiotic susceptibilities of isolates of S. aureus obtained against eight different antibiotics including Linezolid were determined using the disc-plate method.

Results: The results showed that 91 (22.8%) of the subjects tested are nasal carriers of S. aureus. The incidences of resistance observed with each of the antibiotics tested were as follow: Erythromycin 83(91.2%), Tetracycline 79(86.8%), Co-trimoxazole 78(86.8%), Cefoxitin 77(84.6%), Linezolid 72(79.1%), Ciprofloxacin 70(76.9%), Augmentin 49(53.8%) and Gentamycin 39 (42.9%).

Conclusion: Treatment of S. aureus infections within the study environment should be based on the results of in vitro susceptibility testing of the isolates. Gentamicin promises to be the best antibiotic for the treatment of disorders associated with Staphylococci in the study area. This is of special importance in an environment within which a very substantial proportion of the isolates are resistant to methicillin and linezolid.

Author(s) Details

Abdulrasheed Abdu
Department of Medical Microbiology and Parasitology, Faculty of Basic Medical Sciences, College of Health Sciences, Niger Delta University, Wilberforce Island, Amassoma, Bayelsa-State, Nigeria.

Prof. Adebayo Lamikanra
Department of Pharmaceutics, Faculty of Pharmacy, Niger Delta University, Wilberforce Island, Nigeria and Faculty of Pharmacy, Obafemi Awolowo University, Ile-Ife, Osun-State, Nigeria.

View Book: http://bp.bookpi.org/index.php/bpi/catalog/book/107
Labels:

Comments

Post a Comment

Popular posts from this blog

Greening Regional Airports: A Vision for Carbon Neutral Infrastructure | Chapter 12 | Contemporary Perspective on Science, Technology and Research Vol. 3

 This study provides an overview of the energy demand of a regional airport, divided into individual time horizons. The electrification of aircraft systems raises the question of whether airports will be among the largest electricity consumers in our infrastructure in the future. Sustainability and especially emission reductions are significant challenges for airports that are currently being addressed. The Clean Sky 2 project GENESIS addresses the environmental sustainability of hybrid-electric 50-passenger aircraft systems in a life cycle perspective to support the development of a technology roadmap for the transition to sustainable and competitive electric aircraft systems. This article originates from the GENESIS research and describes various options for ground power supply at a regional airport. Potential solutions for airport infrastructure with a short (2030), medium (2040), and long (2050) time horizon are proposed. In addition to the environmental and conservation benefi...
Post a Comment
Read more

There is No Standard Model of ZFC and ZFC2 | Chapter 03 | Advances in Mathematics and Computer Science Vol. 1

In this Chapter we obtain a contradictions in formal set theories under assumption that these theories have omega-models or nonstandard model with standard part. An possible generalization of Lob’s theorem is considered. Main results are: (i) ¬Con(ZF C+ ∃ M ZFC st ), (ii) ¬Con(N F+ ∃ M NF st ), (iii) ¬Con(ZF C 2 ), (iv) let k be an inaccessible cardinal then ¬Con(ZF C+ ∃ κ), (v) ¬Con(ZF C+ (V=L)), (vi) ¬Con(ZF+ (V=L)). Author   Details: Jaykov Foukzon Israel Institute of Technology, Haifa, Israel Men'kova Elena Romanovna All-Russian Research Institute for Optical and Physical Measurements, Moscow, Russia Read full article: http://bp.bookpi.org/index.php/bpi/catalog/view/46/221/408-1 View Volume: https://doi.org/10.9734/bpi/amacs/v1
Post a Comment
Read more

Study on Processing Method Influences the Effect of Cassava (Manihot esculenta) Consumption on Blood Lipid Profile in Rats | Chapter 8 | Current Research and Development in Chemistry Vol.1

Cassava is consumed in many tropical countries and is fast becoming the major raw material of many diets, especially in the bakery, brewery and pharmaceutical industries. In a study to determine the effects of various formulations of Cassava feeds on blood lipid profile in rats. Forty adult Wistar rats weighing between 120 and 150 g were divided into 4 groups of 10 rats each. The rats were acclimatized for one week; fed with different formulations of Cassava feeds adlibitum, after which the rats were allotted into groups. Group 1 was fed on Garri; group 2 on Cassava flour; group 3 on Tapioca, and the control group (group 4) on normal chow. After 4 weeks, each animal was anaesthetized by exposure to chloroform vapour and blood samples collected by cardiac puncture. Group 1 diet (Garri) significantly increased HDL-cholesterol (HDL-C) concentration and significantly decreased LDL-cholesterol (LDL-C) concentration (p<0.05) compared with the control group. In Group 2 (Cassava flour), t...
Post a Comment
Read more