Influence of Dietary Supplementation of Coated Sodium Butyrate and/or Synbiotic on Growth Performances, Caecal Fermentation, Intestinal Morphometry and Metabolic Profile of Growing Rabbits | Chapter 09 | Research and Development in Agricultural Sciences Vol. 2
Aim:
The aim of the present experiment was to study the synergistic effects of
dietary supplementation with coated slow released sodium butyrate (CM3000®)
and a commercial synbiotic (Poultry-Star®) on the productive
performance and intestinal morphometry of the growing rabbits.
Study Design: Laboratory
experimental design was used in this study.
Place and Duration of Study: The
study was conducted in the experimental rabbitry of Physiology Department,
Faculty of Veterinary Medicine Cairo University, Egypt. The s duration of the
study persists for 70 days.
Methodology: Thirty- two apparently
healthy male New Zealand rabbits with average body weight of 544 ± 9 g were
divided randomly into four dietary treatments at weaning (28th day
of age). The control group (C) was fed on standard basal diet with no
supplementation. Rabbits in the second group (T1) received the same basal diet
supplemented with CM3000® 500 g/ton feed. Animals in the third group
(T2) consumed the basal diet containing Poultry-Star® 500 g/ton
feed. Rabbits in the fourth group (T3) were fed on the basal diet enriched with
mixture of CM3000® and Poultry-Star®, 250 g/ton feed for
each. Feed and water were offered ad-libitum for 70 days experimental period.
Body weight and feed consumption were recorded biweekly to calculate body
weight gain and feed conversion. At the end of the experimental period blood
and caecal content samples were collected from all animals. Ce rtain
haematological metabolic parameters namely, glucose [1] triglycerides [2],
total cholesterol [3] total protein [4], albumen and urea [5]. Caecal content
samples were collected at the end of the experimental period post slaughtering
for determination of caecal fermentation pattern namely, pH, total short chain
fatty acids [6] individual volatile fatty acids [7]and ammonia concentration
[8,9]. Duodenal tissue samples were collected for histomorphometry. The results
revealed that additives used improved significantly live body weight compared
to the control group. Rabbits in T3 group showed the highest body weight gain.
In addition, supplementation of the basal diet with a mixture of additives
revealed significant increase of feed intake. The blood urea level was reduced
significantly in bucks of T1. The rabbits in T3 group recorded the highest
level of blood glucose. Caecal pH revealed a significant decrease in T1 and T3.
The mixture of additives has positive results on the intestinal morphometry.
Conclusion: Coated butyrate and are
capable of improving performance, enhancing intestinal health.
Author(s) Details
Mr. Anthony Kodzo-Grey
Venyo MB ChB FRCS(Ed) FRCSI FGCS Urol. LLM
Department of Urology, North
Manchester General Hospital, Manchester, M8 5RB, United Kingdom.
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