Skip to main content

Para-testicular Liposarcoma: An Update of the Literature | Chapter 01 | New Insights into Disease and Pathogen Research Vol. 4

Less than 200 cases of para-testicular liposarcoma (PTL) have been reported. PTL may present with painless or painful intra-scrotal or inguinoscrotal mass of long duration or recent onset but the most common presentation is a painless mass. Para-testicular liposarcomas does mimic various common intra-scrotal and inguinoscrotal masses, some of which include: inguinal hernia, lipoma, fibroma, fibrosarcoma, leiomyoma, leiomyosarcoma, rhabdomyosarcoma, various types of testicular tumours and other non-common intra-scrotal lesions. The symptoms tend to be non-specific. PTLs tend to be unilateral but bilateral cases have been reported. Radiology imaging would define the features of the lesion. Fine needle aspiration cytology could establish the diagnosis but the diagnosis tends to be established by pathology examination of the excised specimen of the tumour which would show spindled-tumoral cells with atypical features and mitotic activity and lipoblasts. Immunohistochemistry staining studies of the tumour would exhibit positive staining for MDM2, CDK4, S100 and STAT6. PTL is treated by trans-inguinal radical orchidectomy ensuring complete excision of the tumour with tumour-free excision margin plus adjuvant radiotherapy plus / minus adjuvant chemotherapy for localized disease. For metastatic and advanced lesions, radical trans-inguinal orchidectomy plus radiotherapy plus chemotherapy should be undertaken. New chemotherapy options need to be developed to effectively destroy para-testicular liposarcoma tumour cells. All excised innocuous looking intra-scrotal masses that should be submitted for histopathology examination in order not to misdiagnose PTL as benign lipoma. Generally the prognosis of localized PTL tends to be good following radical orchidectomy with complete excision of tumour.

Author(s) Details

Mr. Anthony Kodzo-Grey Venyo MB ChB FRCS(Ed) FRCSI FGCS Urol. LLM
Department of Urology, North Manchester General Hospital, Manchester, M8 5RB, United Kingdom.

View Volume: http://bp.bookpi.org/index.php/bpi/catalog/book/128

Comments

  1. I Want To Appreciate Dr.OYAGU for hs great deeds, I Was Diagnosed With type 2 Herpes Virus Last year,And Was Look For Solution To Be Cured Luckily I Saw Testimonies On How Dr.OYAGU Cure Herpes Virus I Decided To Contact Dr.OYAGU I Contacted Him He Prepared A Herbal Medicine Portion And Sent It To Me,I Started The Herbal Medicine For My Health.He Gave Me Step By Step Instructions On How To Apply It, When I Applied It As Instructed, I Was Cured Of This Deadly Herpes Within 2 weeks, I Am Now Herpes Negative.My Brother And Sister I No That There Are So Many People That Have There Same Herpes Virus Please contact Dr OYAGU To Help You Too,And Help Me To Thank Dr.OYAGU For Cure Me, I’m Cured By Dr. OYAGU Herbal Medicine,His Contact Email:oyaguspellcaster@gmail.com

    Or Cell Whatsapp Number +2348101755322 thank you .....

    ReplyDelete

Post a Comment

Popular posts from this blog

Consensus Summit: Lipids and Cardiovascular Health in the Nigerian Population | Chapter 09 | Current Trends in Food Science Vol. 1

Aims: To issue a consensus statement on Lipids and Cardiovascular Health and the impact of their interrelationship in Nigerian Population. Study Design: Experts from a range of relevant disciplines, deliberated on different aspects of Lipids and Cardiovascular Health in the Nigerian Population at a Summit. Place and Duration of Study: The Summit was held in April 2016 at the Nigerian Institute of Medical Research. Methodology: Presentations were made on central themes after which expert participants split into four different groups to consider the questions relevant to different sub themes of the title. Consensus was arrived at, from presentations of groups at plenary. Conclusion: With the increase in the prevalence of NCDs, especially Cardiovascular Disease in Nigeria, and the documented evidence of deleterious effects of lipids, the expert panel called for an urgent need to advocate for the general public and health professionals to make heart-friendly

A Review on Gongronema latifolium, an Extremely Useful Plant with Great Prospects | Chapter 11 | Recent Advances in Biological Research Vol. 3

Gongronema latifolium is a plant that has a wide range of nutritional and ethnomedical uses in different tropical African communities. Scientific reports on the chemical composition and bioactivity (anti-inflammatory, antimicrobial, antidiabetic, antioxidant, anticancer and allelopathic properties) of the plant material by different authors are discussed in this review. Future prospects of the plant extracts in the areas of herbal formulations, food preservation, alcoholic fermentation and beer production, drug discovery and allelopathy are also highlighted. Author   Details: Olugbenga Morebise Faculty of Basic Medical Sciences, All Saints University School of Medicine, Roseau, Commonwealth of Dominica. Read full article: http://bp.bookpi.org/index.php/bpi/catalog/view/50/403/433-1 View Volume: https://doi.org/10.9734/bpi/rabr/v3

Dictionary of Medicinal Plants - Scientific Names, Family and Selected Vernacular (English, Sinhala, Sanskrit and Tamil) Names | Book Publisher International

Medicinal plants have been known for centuries and are highly valued all over the world as a rich source of therapeutic agents of medicinal plants for public health care in developing nations [65]. Even today, the WHO estimates that up to 80 percent of the world population still relies mainly on traditional remedies such as herbs for their primary health care [13]. Ahmed et al. mentioned that according to a survey conducted by W.H.O., traditional healers treat 65% patients in Sri Lanka and 80% in India [3]. According to the WHO, around 21,000 plant species have the potential for being used as medicinal plants. Different ethnic and different language speaking peoples are living in Asian countries. Plants are commonly known by their local names in every part of the world. These local names play a very important role in ethno-botanical study of a specific tribe or region. Local names given to plants by indigenous people in their local dialects often reflect a broad spectrum of inf