Peptide Based Tuberculosis Treatment: A Million Dollar Question | Chapter 08 | Emerging Research in Medical Sciences Vol. 3
Tuberculosis (TB) is a deadly tropical
disease that is mainly caused by Mycobacterium tuberculosis. The pathogen is
known to invade and replicate inside the host’s macrophage. Due to the emerging
dilemma of multi-drug resistant TB and extensively-drug resistant TB, the
exigency for finding new TB drugs is an obligation now. Among the propitious
anti-tubercular agents studied in the past few decades, peptides from
diversified sources have been substantiated to be persuasive with multiple
advantages such as low immunogenicity, selective affinity to bacterial
negatively charged cell envelopes and most importantly divergent mechanisms of
action. This chapter highlights the role of prime peptides exploited from
several other unplumbed sources as anti-tubercular agents.
Author(s) Details
Ameer Khusro
Department of Plant Biology
and Biotechnology, Loyola College, Nungambakkam, Chennai-34, India.
Chirom Aarti
Department of Plant Biology
and Biotechnology, Loyola College, Nungambakkam, Chennai-34, India.
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