A Comparison of Rheumatoid Arthritis Patients in Kuwait with Other Populations: Results from the KRRD Registry | Chapter 07 | Innovations in Medicine and Medical Research Vol. 1

Objective: Data on rheumatoid arthritis (RA) in Kuwait and The Middle East is scarce. Available data from Western countries may not be representative of the region. We describe RA patients in Kuwait and compare them with other RA populations and with Kuwaiti general population.

Methods: Adult RA patients from Kuwait Registry for Rheumatic Diseases (KRRD), the first RA registry in The Middle East, were studied from February 2013 through February 2015. Demographic, clinical and serologic data were compared with other RA populations and with Kuwaiti general population.

Results: 835 patients were enrolled, 62.3% female. Mean age 50.6±12 years and disease duration 6.1±6 years. RA was diagnosed at a mean age of 44.9±12 years. 17.1% had family history of autoimmune rheumatic diseases. 3.1% had rheumatoid nodules. Rheumatoid factor (RF) and anti-citrullinated peptide (ACPA) were detected in 75.6% and 57.8%, respectively. Both were positive in 49% (r=0.287, p=0.001). ANA was positive in 19.1%. Both ACPA and a combination of positive RF and ACPA were more in males (p=0.017, 0.004 respectively), whereas ANA was more in females (p=0.01). One third of male patients were smokers versus 1.9% of females. Smoking was correlated to RF (p=0.009) and ACPA (p=0,002). Difference in ACPA between genders was statistically explained by the predominance of smoking in males. Comorbidities included diabetes mellitus (DM) (20.8%), hypertension (20.2%), hyperlipidemia (10.5%) and coronary artery disease (CAD) (3.1%). 4 cases of cancer were reported.

Conclusion: RA population in Kuwait includes less women than other RA populations but more than Kuwaiti general population. Family history is more common. A higher positive ACPA in males was explained by smoking difference. Hypertension and hyperlipidemia were less reported than in both Kuwaiti general population and other RA populations. CAD was similar to other RA populations. DM was more reported, reflecting its high background prevalence in Kuwait.

Author(s) Details

Dr. Adeeba Al-Herz

Amiri Hospital, Kuwait City, Kuwait.

Adel Al-Awadhi

Department of Medicine, Faculty of Medicine, Kuwait University, Kuwait.

Khulood Saleh

Farwania Hospital, Farwaniya Governorate, Kuwait

Waleed Al-Kandari

Farwania Hospital, Farwaniya Governorate, Kuwait.

Eman Hasan

Amiri Hospital, Kuwait City, Kuwait.

Aqeel Ghanem

Mubarak Al-Kabeer Hospital, Hawally Governorate, Kuwait.

Fatemah Abutiban

Jahra Hospital, Jahra Governorate, Kuwait.

Ahmad Alenizi

Jahra Hospital, Jahra Governorate, Kuwait.

Mohammed Hussain

Amiri Hospital, Kuwait City, Kuwait.

Yaser Ali

Mubarak Al-Kabeer Hospital, Hawally Governorate, Kuwait.

Ahmad Khadrawy

Farwania Hospital, Farwaniya Governorate, Kuwait.

Ammad Fazal

Farwania Hospital, Farwaniya Governorate, Kuwait.

Khaled Mokaddem

Amiri Hospital, Kuwait City, Kuwait.

Beena Aftab

Jahra Hospital, Jahra Governorate, Kuwait.

Najaf Haider

Jahra Hospital, Jahra Governorate, Kuwait.

Ajaz Zaman

Mubarak Al-Kabeer Hospital, Hawally Governorate, Kuwait.

Ghada Mazloum

Mubarak Al-Kabeer Hospital, Hawally Governorate, Kuwait.

Youssef Bartella

Amiri Hospital, Kuwait City, Kuwait.

Sally Hamed

Amiri Hospital, Kuwait City, Kuwait.

Ahmed Al-Saber

Department of Mathematics and Statistics, University of Strathclyde, Glasgow, Scotland.

View Volume: http://bp.bookpi.org/index.php/bpi/catalog/book/139

Greening Regional Airports: A Vision for Carbon Neutral Infrastructure | Chapter 12 | Contemporary Perspective on Science, Technology and Research Vol. 3

This study provides an overview of the energy demand of a regional airport, divided into individual time horizons. The electrification of aircraft systems raises the question of whether airports will be among the largest electricity consumers in our infrastructure in the future. Sustainability and especially emission reductions are significant challenges for airports that are currently being addressed. The Clean Sky 2 project GENESIS addresses the environmental sustainability of hybrid-electric 50-passenger aircraft systems in a life cycle perspective to support the development of a technology roadmap for the transition to sustainable and competitive electric aircraft systems. This article originates from the GENESIS research and describes various options for ground power supply at a regional airport. Potential solutions for airport infrastructure with a short (2030), medium (2040), and long (2050) time horizon are proposed. In addition to the environmental and conservation benefi...

Risk Factors for Postpartum Psychiatric Disorders. A Review of the Literature | Chapter 8 | New Visions in Medicine and Medical Science Vol. 4

Objective: The aim of this study was to explore the risk factors for the development of postpartum psychiatric disorders through international literature. Materials and Methods: Throughout many articles in PubMed, Google scholar and PsycInfo, a great amount of recent data was gathered to identify the disorders that are most common as well as their risk factors. Results: After childbirth, most commonly women experience postpartum depression, anxiety disorders, post-traumatic stress disorder and postpartum psychosis. All the disorders have many similar risk-factors with the main one being preexisting psychiatric disorder and many similar symptoms too. Conclusions: Women after childbirth are at risk of experience many psychiatric disorders, such as postpartum distress, postpartum post traumatic stress disorder and even more rarely postpartum psychosis. It is important to provide comprehensive support to ensure the well-being of both the mother and the infant and this will b...

Alkali Element Modification of Glucose Molecules as a Method to Dissolve Cancer Cells | Chapter 12 | New Visions in Medicine and Medical Science Vol. 4

The present study highlights about alkali element modification of glucose molecules as a method to dissolve cancer cells. The central regulation of the mechanisms governing cell proliferation has little effect on cancer cells. Cancer cells are entirely independent of the central command and divide and proliferate on their own, making it challenging to activate their response mechanism. Precisely, this is the reason why they are at risk to the health of humans and/or any biological entities. Instead of trying to reconnect the central command of the growth control mechanism to cancer cells that are already out of the range, we present a method of using the cancer cell’s own irresponsive and uncontrolled growth mechanism to their disadvantage and destroy the cancer cells. We found that this is achievable in an atomic/molecular level study of the glucose molecule, which is the primary food source used for growth and energy generation by all cells in the body, including the cancer cel...

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