Frequencies of Genotypes and Alleles of the K232A Substitution in the DGAT1 Gene in Four Cattle Breeds of Russian Selection | Chapter 09 | Advances in Agriculture and Fisheries Research Vol. 1
The enzyme DGAT1 is involved in the
synthesis of triglycerides. The most well-known polymorphic variant of the
DGAT1 gene is substitution of lysine with alanine at position 232 of the
protein (K232A). The 232K allele is associated with increased enzyme activity
and a higher content and yield of fat in milk. There is less data on the
frequencies of alleles of this replacement in different breeds in literature.
In our research work, we analyzed the frequencies of genotypes and alleles of
the K232A substitution in the DGAT1 gene in 4 breeds of Russian selection:
Black-and-white Holsteinized, Kalmyk, Ayshire and Angus. We demonstrated that
the K allele is minor in the populations of the analyzed cattle breeds.
Author(s) Details
Dr. Eugene Klimov
Center of Experimental Embryology
and Reproductive Biotechnologies, Moscow, Russian Federation and Lomonosov Moscow State University, Faculty of
Biology, Moscow, Russian Federation.
Anna Arkhipova
Center of Experimental Embryology
and Reproductive Biotechnologies, Moscow, Russian Federation.
Svetlana Kovalchuk
Center of Experimental Embryology
and Reproductive Biotechnologies, Moscow, Russian Federation.
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