Synthesis and Characterization of 4-[(3,5-Dimethyl-1H-pyrazol-1-yl)Methyl]-4-Methyl-2-Phenyl-4,5-Dihydrooxazole| Chapter 11 | Theory and Applications of Chemistry Vol. 4
The compound, 4-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]-4-methyl-2-phenyl-4,5-dihydrooxazole
2 was prepared in high yield, through nucleophilic substitution reaction
of the O-tosyloxazoline derivative 1, by heating in dimethyl sulfoxide
(DMSO) and in presence of KOH as base. The structure of the synthesized
compound was established on the basis of NMR spectroscopy (1H, 13C),
MS data and elemental analysis.
Author(s) Details
Sara Hajib
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