Formulation Development of Naturally Sweet Herbal Oral Health Drinks and Its HPTLC Analysis | Chapter 15 | Trends in Pharmaceutical Research and Development Vol. 1
Ashwagandha,
Tulsi, Mulethi, Awala, Shatavari, Gokharu, Arjun, Giloy, Safed musli, Kalimirchi,
Haldi, Jaiphal can be used as an active ingredients and aqueous extract of
Stevia rebaudiana as natural sweetener with nutraceutical in health dinks. The
product can be developed by treating concentrates of each crude drug with
purified water. TLC profile, HPTLC method development and validation can be
carried out using Gallic acid as a standard. A new simple, sensitive,
selective, precise and robust HPTLC method for analysis of Gallic acid in
health drink can be developed. Precoated silica health drink aluminium plate
60F-254 (20 × 10 cm) with 200 µm thickness can be used as stationary phase
while toluene: ethyl acetate: formic acid: ethanol (6: 4: 0.3: 0.4) system can
be developed as a mobile phase. Spectrum analysis showed the same Rf values and
spectrum pattern of standard and sample. The method can be validated by using
accuracy, precision, linearity, robustness, ruggedness and recovery as
applicable parameters. The developed method can be quite good and most
sensitive for the present products. The unpleasant and bitter taste of the
product can be masked by different concentrations of aqueous extract of Stevia.
Sweetness potency can be determined by taste evaluation method. 1% Stevia
extract may be sufficient to produce most palatable and acceptable sweet
preparation.
Author (s) Details
Dr. V. R. Salunkhe
Department of Pharmacognosy, Rajarambapu College of Pharmacy, Kasegaon, Dist. Sangli, Maharastra, India.
View Book :- http://bp.bookpi.org/index.php/bpi/catalog/book/156
Author (s) Details
Dr. V. R. Salunkhe
Department of Pharmacognosy, Rajarambapu College of Pharmacy, Kasegaon, Dist. Sangli, Maharastra, India.
View Book :- http://bp.bookpi.org/index.php/bpi/catalog/book/156
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