Skip to main content

Relation of the Prevalence of Hepatitis B and C Viruses with Tumor Necrosis Factor- α among Patients in Babylon Province | Chapter 7| Theory and Applications of Microbiology and Biotechnology Vol. 3

Background: Hepatitis is a liver disease caused by infectious and non-infectious agents. Hepatitis B and C are global health problem. Hepatitis B (HBV) and C virus (HCV) infections are usually occur in the population due to their divers mode of transmission through blood. Objectives: This study aimed to assess the prevalence of hepatitis B and C virus among population in Babylon province and evaluation of the levels of the TNF-alpha in infected patients with hepatitis B and C. Methods: The study was conducted on individuals referred to the Central Public Health Laboratory to detected the prevalence of HBV and HCV infections in Babylon province. A total of 6061 samples was involved in this study, they surveyed by VIDAS test for demonstration of both viruses, then confirmed by real- time PCR. Concentration of TNF- α was measured in patients with hepatitis B and C and control group (Control group included healthy individuals with no history of renal or liver diseases and negative results for HBV and HCV test) by using ELISA test. Results: A total of 6061 individual were examine, amongst them, 18 (0.29%) were positive for HBV and 16 (0.26%) were positive for HCV by both VIDS test and real-time PCR.  Most of HBV infections seen among hemodialysis patients followed by haemophila, while most HCV infections seen among thalasemia and haemophila patients than others groups. The prevalence of both viruses was higher among male than female, and in urban than rural rejoin. Most of HBV infections were high in individual with age ranging between 20-29 and 30-39 years, while most HCV infections in individual with age ranging between 20-29 years, although it is statistically insignificant.  The TNF- α mean serum level was significantly higher in individual with HBV and HCV infection (68.7±12.84 pg/mL) and (89.1±22.017) as compared with control group (43.1±5.87 pg/mL). Conclusion: The prevalence of hepatitis B and C virus was relatively low. There are increasing level of TNF-α in the serum of patients with viral hepatitis B and C. 
Author(s) Details

Rasha Hadi Saleh
Department of Clinical and Laboratory Sciences, College of Pharmacy, Babylon University, Iraq.

View Book :- http://bp.bookpi.org/index.php/bpi/catalog/book/154

Labels:

Comments

Post a Comment

Popular posts from this blog

Greening Regional Airports: A Vision for Carbon Neutral Infrastructure | Chapter 12 | Contemporary Perspective on Science, Technology and Research Vol. 3

 This study provides an overview of the energy demand of a regional airport, divided into individual time horizons. The electrification of aircraft systems raises the question of whether airports will be among the largest electricity consumers in our infrastructure in the future. Sustainability and especially emission reductions are significant challenges for airports that are currently being addressed. The Clean Sky 2 project GENESIS addresses the environmental sustainability of hybrid-electric 50-passenger aircraft systems in a life cycle perspective to support the development of a technology roadmap for the transition to sustainable and competitive electric aircraft systems. This article originates from the GENESIS research and describes various options for ground power supply at a regional airport. Potential solutions for airport infrastructure with a short (2030), medium (2040), and long (2050) time horizon are proposed. In addition to the environmental and conservation benefi...
Post a Comment
Read more

Study on Processing Method Influences the Effect of Cassava (Manihot esculenta) Consumption on Blood Lipid Profile in Rats | Chapter 8 | Current Research and Development in Chemistry Vol.1

Cassava is consumed in many tropical countries and is fast becoming the major raw material of many diets, especially in the bakery, brewery and pharmaceutical industries. In a study to determine the effects of various formulations of Cassava feeds on blood lipid profile in rats. Forty adult Wistar rats weighing between 120 and 150 g were divided into 4 groups of 10 rats each. The rats were acclimatized for one week; fed with different formulations of Cassava feeds adlibitum, after which the rats were allotted into groups. Group 1 was fed on Garri; group 2 on Cassava flour; group 3 on Tapioca, and the control group (group 4) on normal chow. After 4 weeks, each animal was anaesthetized by exposure to chloroform vapour and blood samples collected by cardiac puncture. Group 1 diet (Garri) significantly increased HDL-cholesterol (HDL-C) concentration and significantly decreased LDL-cholesterol (LDL-C) concentration (p<0.05) compared with the control group. In Group 2 (Cassava flour), t...
Post a Comment
Read more

Ethnopharmacological Survey among Traditional Medicine Practitioners in Abidjan (Côte d'Ivoire) for the Management of Pathologies such as Malaria, ENT Diseases, Diarrhea, Typhoid Fever and Anemia | Chapter 05 | New Horizons in Medicine and Medical Research Vol. 8

 Traditional Medicine Practitioners (TMPs) of Côte d'Ivoire are familiar with the therapeutic herbs. Medicinal plants have been shown to be useful in the treatment of common diseases such as malaria (KROA, 2004) and diabetes (N'GUESSAN et al, 2013) in several studies and scientific study. In the Abidjan District, the current policy is to integrate traditional medicine and pharmacopoeia into the national health system in order to improve population health coverage, particularly in the management of commonly encountered diseases such as malaria, ENT diseases, diarrhoea, typhoid fever, and anaemia. This research aims to increase the use of traditional medicine and pharmacopoeia in the national health system. Over the course of three months, fifty (50) PMTs in the District of Abidjan participated in this study. Plant therapists accounted for 30 of the 50 PMTs polled at the end of the study, or 60%. Traditional medicine centres use 61 types of medicinal plants from 36 famili...
Post a Comment
Read more