COVID-19 Disease on 700 Chronic Dialysis Patients from Ecuadorian Highlands: An Observational Study | Chapter 3 | New Frontiers in Medicine and Medical Research Vol. 11

Introduction: In December of this year, the first cases of Covid-19 sickness were documented. The pandemic has spread throughout the world by March 2021, with 114.217.365 cases and 2.533014 deaths, including 286.155 cases and 15.811 deaths in Ecuador. After one year of pandemic, the researchers wanted to highlight the impact of COVID-19 disease on 700 chronic dialysis patients from Ecuador's highlands, representing roughly 7% of the country's dialysis population.

Materials and Methods: 700 Latino chronic dialysis patients from five different cities in Ecuador's highlands participated in an observational prospective multicenter study.

From February 1, 2020, through January 31, 2021, patients were tracked. COVID-19 signs were discovered, and the disease was only confirmed by PCR testing of nasopharyngeal swabs. If oxygen saturation was less than 90% at the time of presentation (LOS), the disease was classified as severe, moderate if symptoms were present but not at LOS, and asymptomatic if no symptoms were seen. The length of stay in the hospital, the time between a negative PCR and death, as well as laboratory results, were all kept track of.

Two hundred and five patients (29%) exhibited COVID-19 disease symptoms; 115 patients (16%) tested positive, with 60 percent of them being men (p=0.03). Twenty-five patients died as a result of their illness (22 percent ). Being over 64 years old, having a saturation of less than 90%, and having a severe illness presentation (all p=0.03), as well as having previous lung pathology and hospitalisation (all p=0.01), were all connected to mortality. In 74 patients (64 percent), hospitalisation was required, with an average stay of 11 days (4-15), days until death while hospitalisation of 12 days (4-19), and time until a negative PCR of 20 days (10-25). The symptomatology lasted for 16 days (11-26).

Conclusion: COVID-19 disease is more common in men, and it has led in a 22 percent increase in the death rate among chronic dialysis patients. Patients over 64, those with preexisting pulmonary disease, and those with a longer LOS at presentation have a greater chance of death, necessitating more frequent follow-up in this population. COVID-19 has a significant health-care burden in the dialysis community, emphasising that dialysis patients and professionals involved in their care should be vaccinated to reduce disease-related mortality, infections, and health-care expenses.

Author (S) Details

Santacruz Juan
Nephrology and Dialysis Unit “Clínica de Los Riñones Menydial-Quito”, Quito, Ecuador.

Vasquez Ana
Nephrology and Dialysis Unit “Clínica de Los Riñones Menydial-Quito”, Quito, Ecuador.

Reinoso Paulo
Nephrology and Dialysis Unit “Clínica de Los Riñones Menydial-Quito”, Quito, Ecuador.

Sulbaran Carlotta
Nephrology and Dialysis Unit “Clínica de Los Riñones Menydial-Quito”, Quito, Ecuador.

Santacruz Gabriela
Nephrology and Dialysis Unit “Clínica de Los Riñones Menydial-Quito”, Quito, Ecuador.

Arevalo Paola
Nephrology and Dialysis Unit “Clínica de Los Riñones Menydial-Quito”, Quito, Ecuador.

Valencia Alex
Nephrology and Dialysis Unit “Clínica de Los Riñones Menydial-Riobamba”, Riobamba, Ecuador.

Anaya Griselle
Nephrology and Dialysis Unit “Clínica de Los Riñones Menydial-Riobamba”, Riobamba, Ecuador.

Avalos Cesar
Nephrology and Dialysis Unit “Clínica de Los Riñones Menydial-Riobamba”, Riobamba, Ecuador.

Toalongo Yadira
Nephrology and Dialysis Unit “Clínica de Los Riñones Menydial-Riobamba”, Riobamba, Ecuador.

Avalos Francis
Nephrology and Dialysis Unit “Clínica de Los Riñones Menydial-Riobamba”, Riobamba, Ecuador.

Tamayo Oswaldo
Nephrology and Dialysis Unit “Clínica de Los Riñones Menydial-Tulcán”, Tulcán, Ecuador.

Burbano Daniel
Nephrology and Dialysis Unit “Clínica de Los Riñones Menydial-Tulcán”, Tulcán, Ecuador.

Yar Hector
Nephrology and Dialysis Unit “Clínica de Los Riñones Menydial-Tulcán”, Tulcán, Ecuador.

Rodríguez, Norlan
Nephrology and Dialysis Unit “Clínica de Los Riñones Menydial-Ambato”, Ambato, Ecuador.

Quevedo Ángel
Nephrology and Dialysis Unit “Clínica de Los Riñones Menydial-Ambato”, Ambato, Ecuador.

Almagro Jenny
Nephrology and Dialysis Unit “Clínica de Los Riñones Menydial-Ambato”, Ambato, Ecuador.

Guacho José
Nephrology and Dialysis Unit “Clínica de Los Riñones Menydial-Ambato”, Ambato, Ecuador.

Chicaiza Ana
Nephrology and Dialysis Unit “Clínica de Los Riñones Menydial-Ibarra”, Ibarra, Ecuador.

Vera Jairo
Nephrology and Dialysis Unit “Clínica de Los Riñones Menydial-Ibarra”, Ibarra, Ecuador.

Rosales Ubelis
Nephrology and Dialysis Unit “Clínica de Los Riñones Menydial-Ibarra”, Ibarra, Ecuador.

Santacruz Cristóbal
Nephrology and Dialysis Unit “Clínica de Los Riñones Menydial-Quito”, Quito, Ecuador.

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