Skip to main content

Early Assessment of the Risk of Developing Subclinical Hypothyroidism and Cardiovascular Risk in Patients with Nonalcoholic Fatty Liver Disease | Chapter 7 | New Frontiers in Medicine and Medical Research Vol. 11

Background: It is well established that subclinical hypothyroidism (SH) might exacerbate the progression of non-alcoholic fatty liver disease (NAFLD) (NAFLD). NAFLD, in turn, encourages thyroid gland hypofunction. Patients with SH have a higher risk of cardiovascular events, although research on SH screening recommendations is conflicting and inadequate.

The goal of this study was to determine the risk of developing subclinical hypothyroidism (SH) in patients with non-alcoholic fatty liver disease (NAFLD) who had a different risk of cardiovascular complications, as well as the relationship between a high risk of developing SH and major cardiovascular factors (CV). Methods and materials: 298 patients with NAFLD who had one or more CV risk factors (arterial hypertension, smoking, hypercholesterolemia) and different levels of CV risk factors on the SCORE scale participated in a one-stage clinical research. A standard questionnaire was given to all patients, and HRQ conducted a thyroid status investigation.

According to the level of overall CV risk for SCORE, patients were classified into three groups: Low/moderate CV risk was 33.9 percent, high CV risk was 41.9 percent, and extremely high CV risk was 24.2 percent. The majority of the participants were between the ages of 50 and 59, and 60 and 69. 22.2 percent of patients in the 40-49 year age group had a high CV risk, 28% of men in the 50-59 year age range had a moderate CV risk, and 49.7% of older patients had a very high CV risk. According to the results of an HRQ questionnaire survey, 34.9 percent of patients have a low risk of developing hypertension, 48.9 percent have a moderate risk, and 16.1 percent have a high risk. According to the HRQ questionnaire, people who have a very high CV risk on the SCORE scale also have a high probability of acquiring the SH. Early signs of thyroid status problems should be discovered in individuals with one or more of the above CV risk factors, and the risk of developing hypertension should be examined. This strategy aids in the accurate assessment of the risk of SH in patients with NAFLD and the creation of primary preventative strategies.


Author (S) Details

Olena Kolesnikova
Government Institution «L.T.Malaya Therapy National Institute of the National Academy of Medical Sciences of Ukraine, Kharkiv, Ukraine.

Valeriya Nemtsova
Kharkiv National Medical University, Kharkiv, Ukraine.

Anna Isayeva
Government Institution «L.T.Malaya Therapy National Institute of the National Academy of Medical Sciences of Ukraine, Kharkiv, Ukraine.


View Book :- https://stm.bookpi.org/NFMMR-V11/article/view/3693


Labels:

Comments

Post a Comment

Popular posts from this blog

Greening Regional Airports: A Vision for Carbon Neutral Infrastructure | Chapter 12 | Contemporary Perspective on Science, Technology and Research Vol. 3

 This study provides an overview of the energy demand of a regional airport, divided into individual time horizons. The electrification of aircraft systems raises the question of whether airports will be among the largest electricity consumers in our infrastructure in the future. Sustainability and especially emission reductions are significant challenges for airports that are currently being addressed. The Clean Sky 2 project GENESIS addresses the environmental sustainability of hybrid-electric 50-passenger aircraft systems in a life cycle perspective to support the development of a technology roadmap for the transition to sustainable and competitive electric aircraft systems. This article originates from the GENESIS research and describes various options for ground power supply at a regional airport. Potential solutions for airport infrastructure with a short (2030), medium (2040), and long (2050) time horizon are proposed. In addition to the environmental and conservation benefi...
Post a Comment
Read more

Risk Factors for Postpartum Psychiatric Disorders. A Review of the Literature | Chapter 8 | New Visions in Medicine and Medical Science Vol. 4

  Objective: The aim of this study was to explore the risk factors for the development of postpartum psychiatric disorders through international literature. Materials and Methods: Throughout many articles in PubMed, Google scholar and PsycInfo, a great amount of recent data was gathered to identify the disorders that are most common as well as their risk factors. Results: After childbirth, most commonly women experience postpartum depression, anxiety disorders, post-traumatic stress disorder and postpartum psychosis. All the disorders have many similar risk-factors with the main one being preexisting psychiatric disorder and many similar symptoms too. Conclusions: Women after childbirth are at risk of experience many psychiatric disorders, such as postpartum distress, postpartum post traumatic stress disorder and even more rarely postpartum psychosis. It is important to provide comprehensive support to ensure the well-being of both the mother and the infant and this will b...
Post a Comment
Read more

Alkali Element Modification of Glucose Molecules as a Method to Dissolve Cancer Cells | Chapter 12 | New Visions in Medicine and Medical Science Vol. 4

  The present study highlights about alkali element modification of glucose molecules as a method to dissolve cancer cells. The central regulation of the mechanisms governing cell proliferation has little effect on cancer cells. Cancer cells are entirely independent of the central command and divide and proliferate on their own, making it challenging to activate their response mechanism. Precisely, this is the reason why they are at risk to the health of humans and/or any biological entities. Instead of trying to reconnect the central command of the growth control mechanism to cancer cells that are already out of the range, we present a method of using the cancer cell’s own irresponsive and uncontrolled growth mechanism to their disadvantage and destroy the cancer cells. We found that this is achievable in an atomic/molecular level study of the glucose molecule, which is the primary food source used for growth and energy generation by all cells in the body, including the cancer cel...
Post a Comment
Read more