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Study on Synthesis and Biologically Important of 2-Mercaptobenthiazole (MBT)-clubbed Chalcone Derivatives | Chapter 13 | New Innovations in Chemistry and Biochemistry Vol. 2

In this study, a base catalysed technique was used to create chalcone of (E) -4-(3-(4-hydroxyphenyl)acryloyl) -5-methyl-2(p-tolyl) -1H-pyrazol-3(2H) -one (II) interacted with S-benzo[d] derivatives thiol-2yl-2-chloroethanethioate (Ia-f) led in the production of (E)-S-benzo[d] derivatives. 2-(4-(3-(5-methyl-3oxo-2-thiazol-2-yl thiazol-2-yl thiazol-2-yl thiazol-2-yl thiazol-2-y (p-tolyl) -2,3-dihydro-1H-pyrazol-4-yl) spectrum characterization such as IR, 1H NMR, LC-MS, and elemental analysis verified -3-oxoprop-1-en-1-yl)phenoxy)etanethioate(IIIa-f). Antimicrobial characteristics of the compounds were tested against a wide range of Gram-positive and Gram-negative bacteria, as well as fungi. Compounds 3c and 3e are quite active. Spectral data was used to characterise all of the produced substances.

 

Author (S) Details

Falguni G. Bhabhor
Department of Chemistry, Navjivan Science College, Dahod (GUJ), India.

Satish Khadia
Department of Chemistry, Navjivan Science College, Dahod (GUJ), India and National medicinal plant board, Ministry of Ayush, New Delhi, India.

Harish R. Dabhi
Department of Chemistry, Navjivan Science College, Dahod (GUJ), India.


View Book :- https://stm.bookpi.org/NICB-V2/article/view/3590

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