Determining the Effectiveness of Addition of Drug Teneligliptin to Metformin, Glimepiride, Pioglitazone Combination in Type II Diabetic Patients | Chapter 06 | New Horizons in Medicine and Medical Research Vol. 1
Diabetes is a widespread chronic disease that has spread to epidemic proportions in almost every developed and developing country. Diabetes is the leading cause of death in the world, affecting about 400 million people.
Aims and
Objectives: To investigate the efficacy of combining Teneligliptin with
Metformin, Glimepiride, and Pioglitazone in type 2 diabetic patients.
Methodology: This
was a one-year cross-sectional study on type II diabetic patients conducted in
the Department of Medicine at a tertiary health care centre from January 2017
to January 2018. Out of all type II diabetes patients, 40 were randomly
selected for hypoglycemic therapy with the medications Metformin, Glimepiride,
and Pioglitazone. Of these, 20 were continued on the prior treatment (Group B),
while the remaining 20 were given the extra drug Teneligliptin (Group A). The
statistical analysis was carried out using the SPSS 19 version of software and
included an unpaired t-test and a chi-square test.
The average age in
both groups was comparable, i.e. 36.78 6.74 and 38.92 5.87
(p>0.05,t=1.24,df=38), the sex ration was also comparable (p>0.43, X2
=0.43,df=1), and the HbA1C was comparable at 1st Wk. 10 4.56 - 9.87 3.42
(p>0.05, t = 1.023,df=38) and 4th Wk. 8
Author(S) Details
Dilip Pandurang Patil
Department of Medicine, Krishna Institute of Medical Sciences, Deemed to be University, Karad, Maharashtra, India.
View Book:- https://stm.bookpi.org/NHMMR-V1/article/view/6171
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