Study on the Relationship between Macrovascular and Microvascular Hemodynamics | Chapter 14 | New Horizons in Medicine and Medical Research Vol. 8
The goal of this research is to see if there is a link between macrovascular hemodynamic status and microvascular hemodynamic parameters in periodontal disease patients. The interactions between the macrovasculature and microvasculature have received little attention, but a better knowledge of these vessels' interconnections could lead to new therapeutic and management targets. Seventeen adult patients are voluntarily recruited at the Dentistry Department of the "Mater Domini" University of Catanzaro, with sampling that determines the lipid profile, blood glucose, inflammatory mediators, and blood plasma viscosity: anamnesis, blood pressure measurement, and detection of anthropometric parameters: eco-Doppler of the carotid and brachial arteries with noninvasive hemodynamic measurements and evaluation of inflammation and phlegm The locations with a high probing depth differ from healthy ones in that they had poor oxygen saturation and a significant rise in tissue edoema, although there was no link between macro- and microvascular values. As probing depth increased, there was a correlation between low oxygen saturation levels and tissue edoema values; however, no correlation between macrovascular hemodynamic status and microvascular hemodynamics indices was discovered, most likely due to the heterogeneity of the population studied, the small sample size, and the small number of data collected. It's likely that the two circulatory districts were not firmly connected in gingival pathology, and that the systemic inflammation was the sole thing that caused the carotid hemodynamic condition to worsen in patients with periodontal disease due to the growth of the local gingivopathy.
Author(S) Details
M. M. Figliuzzi
Department of Health and Oral Sciences Periodontology Clinic, Medicine and Surgery School, “Magna Graecia” University of Catanzaro, Catanzaro, Italy.
S. Sestito
Department of Health and Oral Sciences Periodontology Clinic, Medicine and Surgery School, “Magna Graecia” University of Catanzaro, Catanzaro, Italy.
D. Pacifico
Department of Health and Oral Sciences Periodontology Clinic, Medicine and Surgery School, “Magna Graecia” University of Catanzaro, Catanzaro, Italy.
L. Parentela
a Department of Health and Oral Sciences Periodontology Clinic, Medicine and Surgery School, “Magna Graecia” University of Catanzaro, Catanzaro, Italy.
Carlo Rengo
University of Naples “Federico II”, Napoli, Italy.
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