Phenomenon of Bacterial Pathogenicity as a Function of Bo-molecules | Chapter 12 | Recent Advances in Biological Research Vol. 3
The bacterial pathogenicity phenomenon
is the poly-functional biological potency of germs that are realized by factors
(determinants) of pathogenicity (PF) in multi-cellular organism.
Biological functions are responsible
for bacterial pathogenicity in a multi-cellular host organism: the adhesive
function, the function of invasion and penetration into the cell, the function
of evasion of host defense, and the damage function. Factors of pathogenicity
are representative bio-molecules possessed different functional activity. The
ligand - receptor interaction of bacterial PF and receptors on eukaryotic cells
is the basis of specific lesions caused by the pathogen.
Author Details:
Yurii V. Ezepchuk
The
Gamaleya Institute for Epidemiology and Microbiology, Moscow, Russia and The
University of Colorado, Denver, USA.
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