Immune Response of Broiler Chicks to Newcastle Disease Vaccine (LaSota), by Different Routes | Chapter 05 | Recent Advances in Biological Research Vol. 5
Aims:
This work was undertaken to study the immune response of broiler chicks to
LaSota vaccine by using different routes of administration.
Study Design: The design used was a
completely randomized design.
Place and Duration of Study: The study was carried out at the Poultry Unit of the Kogi State University Teaching and Research Farm Anyigba, Kogi State, Nigeria. It lasted for 5 weeks.
Methodology: One-hundred-day old
broiler chicks were grouped into 4 of 25 chicks each (A, B, C and D). In the 3rd
week of life, the groups were vaccinated with LaSota by intraocular (i/o),
intramuscular (i/m) and oral (per os) routes respectively while Group D served
as the unvaccinated control group. Five chicks from each group were randomly
selected and bled at 2, 3, 4 and 5 weeks post LaSota vaccination. Their sera
were used for Haemagglutination Inhibition (HI) test.
Results: All the routes used
produced high levels of Haemagglutination Inhibition (HI) antibody titres two
weeks post vaccination. Immunity fell below protective level after 5 weeks post
vaccination.
Conclusion: All the routes in this
study were immunogenic and vaccination failure may not necessarily be due to
the route of administration of vaccine.
Author(s) Details
Mary Ekundayo Sanda
Department of Veterinary
Medicine, Michael Okpara University of Agriculture, Umudike, Nigeria.
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